Structure of PDB 5oql Chain b Binding Site BS01

Receptor Information
>5oql Chain b (length=291) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLRKQARQRRDYLYRRALLLRDAEIAEKRAKLRAALASGKPLDPKIANDK
ELRKDFDYDVSRDIAKEQGEIDIDDEYSELSGIVDPRVLVTTSRDPSSRL
MAFSKEIRLMFPTAIRLNRGNLILPDLVMSAQRERLSDIILLHEHRGTPT
AITISHFPHGPTLMASLHNVVLRADITVSESYPHLIFEGFRTPLGQRVVK
ILKHLFPPRDPTNNAKSGNRVITFVNQDDCIEVRHHVYVRTNYNSVELSE
VGPRFTMRPFSITMGTLENKDADVEWHLSQYTRTGRKKNYF
Ligand information
>5oql Chain 1 (length=1350) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucuccgcggcagcgcaagccg
uuucauacgucgccgcaaucgcgaggggcuccaagcggucgccggcgagc
accaccccagccccgcgccgcccccagcgcaccgcgcgcaggggggccgg
cgcggcaucugggaagacuccuaaggcgcaagggaauaccccgugcgccg
gggguugggcucugugggugcuuggccgcuggccagaccuacuucaaagc
caccggggguaccuaccgguugucucggucgggccuccucuuggggcgcc
uaggcggugucuucgggucgcgugcagccucccguccucgccugccgaca
gcgcucuggggaauucaggaggggaaagcagaugugccccgcggcgagac
uggcgccggacgagcugcuggggcacgcggguacgcuagccgcacgauag
uuaccugguugauucuuagucauaugcuugucucaaagccaugcgucuaa
guauaagcaauuacagcgaaacugcgaauggcucauuaaaucaguuaucg
uuuauuugauaguauggauaaccgugguaauucuagagcuaauacaugcg
uauuuauuagggugauucauaauaacuucucgaaucgcacggccuugcgc
cggcgaugguucauucaaauuucugcccuaucaacuuucgacggcugggu
auuggccagccguggugacaacggguaagagaggagccugagaaacggcu
acuacauccaaggaagggcaggcgccaaauuacccaaucccgacacgggg
agguagugacaauaaauacugauacagggcuccgggucuuguaauuggaa
ugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucugg
ugccagcagccgcgguaauucccuccaauagcguauauugcucguaguug
aaccugauuaauagggacagucgggggcgucaguauucaauugucagagg
ugaaauucuuggauuuauugaagacuaacaacugcgaaagcauucgccaa
ggauguuuucauuaaucaggaacgauuagggaucggacggcguuuauuuu
ugacccguucggcaccuuacgauaaaucaaaauguuugggaguauggucg
caugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
<<.<<<.<<<<<<<<....>>>>>>>>>>>.>.>.<<<<.<..>..>>>>
.........<<<<<<<.<<<<<..<<<<>>>>..>>>>>.>>.>>>>>..
..<..<<<<<..<<<<<<<<<<<<<.<<<<.....>>>>..>>>>>.>>>
>>>>>...>>>>>..>........<<<<<<.<<<.....>>>.>>>>>>.
........................<<<...>>>.................
....<<<<<..<<<<<<<<.....>>>>>.>>>>>>>>.....<<<<<<.
..<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>....
>>>>>>...........................<<<<.<<<<<<<..<.<
<<<..>>>>.>..>>>>>.>>.>>>><<<<.<.....>.>>>>.......
..................<..<<<<<<...<.<<..<<<<.<<<<<....
<<....<<.......>>...>>.>>......<<<.......<<<..<<..
<<....<<<.......<.<..<..<<<.....>>>..>.....>>....<
...<<<<<<.<......>.>>>>>>.....>...<<<<.<<<<.....>>
>>>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<..
.....>>>>>>>>>>>......>>>...>>><<.<<<..........>>>
.>>.<.<<<..>>>.>.>>>>>>........<<<...<<<<<...>>>>.
>>>>..>>...>.>....<<<<<<<<<<<<<...>>>>>>>>.>>>>>..
...<<..<...........>..>>.........<<<<<<.......<<<.
...>>>................>>>>>>..>>>>>>.>.<.<<...<<<.
<<.....>>.....<<<<<.<<...<<<<..<<<.<<<<<<.....<<<.
.....>>>........>>>>>>.>>>.......<<....>>...>>>>..
>>.>>>.>>....>>>...>>.>..<..<<..<<<<<<<<.<<<......
.>>>>>>>>>>>..>>.....<....>....>..................
..<<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>>.<<<<.<<......>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oql 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R10 S93 R94 S97 R99 K105 L109 R116 N118 G120 N121 I123 L124 H143 E144 H145 R146 T150 S166 T183 S185 E186 F266 E281 W282 H283 L284 Q286 T288 R289 T290 K293 K294
Binding residue
(residue number reindexed from 1)		R10 S93 R94 S97 R99 K105 L109 R116 N118 G120 N121 I123 L124 H143 E144 H145 R146 T150 S166 T177 S179 E180 F260 E275 W276 H277 L278 Q280 T282 R283 T284 K287 K288
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034457 Mpp10 complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5oql, PDBe:5oql, PDBj:5oql
PDBsum5oql
PubMed28967883
UniProtG0SE90

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