Structure of PDB 4y9z Chain b Binding Site BS01
Receptor Information
>4y9z Chain b (length=196) Species:
559292
(Saccharomyces cerevisiae S288C) [
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TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAA
DTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVA
GYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEE
TVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
Ligand information
>4y9z Chain 6 (length=3) Species:
32630
(synthetic construct) [
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LAE
Receptor-Ligand Complex Structure
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PDB
4y9z
Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
T1 T20 T21 T22 G47 A49
Binding residue
(residue number reindexed from 1)
T1 T20 T21 T22 G47 A49
Enzymatic activity
Enzyme Commision number
3.4.25.1
: proteasome endopeptidase complex.
Gene Ontology
Molecular Function
GO:0004175
endopeptidase activity
GO:0004298
threonine-type endopeptidase activity
GO:0005515
protein binding
Biological Process
GO:0006508
proteolysis
GO:0010499
proteasomal ubiquitin-independent protein catabolic process
GO:0043161
proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603
proteolysis involved in protein catabolic process
Cellular Component
GO:0000502
proteasome complex
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005839
proteasome core complex
GO:0019774
proteasome core complex, beta-subunit complex
GO:0034515
proteasome storage granule
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4y9z
,
PDBe:4y9z
,
PDBj:4y9z
PDBsum
4y9z
PubMed
26020686
UniProt
P38624
|PSB1_YEAST Proteasome subunit beta type-1 (Gene Name=PRE3)
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