Structure of PDB 8scb Chain aa Binding Site BS01

Receptor Information
>8scb Chain aa (length=98) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVR
DISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPP
Ligand information
>8scb Chain 9 (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgccacuuggauaacugugguaauuc
uagagcuaauacaugccgacgggcgcugacccccuucgcgggggggaugc
gugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgccc
cccguggcggcgacgaccauucgaacgucugcccuaucaacuuucgaugg
uagucgccgugccuaccauggugaccacgggugacggggaaucaggguuc
gauuccggagagggagccugagaaacggcuaccacauccaaggaaggcag
caggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaau
aacaauacaggacucuuucgaggcccuguaauuggaaugaguccacuuua
aauccuuuaacgaggauccauuggagggcaagucuggugccagcagccgc
gguaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagc
ucguaguuggaucuugggagcgggcguccccgccuuuacuuugaaaaaau
uagaguguucaaagcaggcccgagccgccuggauaccgcagcuaggaaua
auggaauaggaccgcgguucuauuuugguuuucggaacugaggccaugau
uaagagggacggccgggggcauucguauugcgccgcuagaggugaaauuc
uuggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuu
ucauuaaucaagaacgaaagucggagguucgaagacgaucagauaccguc
guaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauucc
caugacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggg
ggaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcuuaauuugacucaacacgggaaaccucacc
cggcccggacacggacaggauugacagauugauagcucuuucucgauucc
gugggugguggugcauggccguucuuaguugguggagcgauuugucuggu
uaauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgaccc
ccgagcggucggcgucccccaacuucuuagagggacaaguggcguucagc
cacccgagauugagcaauaacaggucugugaugcccuuagauguccgggg
cugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccgg
caggcgcggguaacccguugaaccccauucgugauggggaucggggauug
caauuauuccccaugaacgaggaauucccaguaagugcgggucauaagcu
ugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuacc
gauuggaugguuuagugaggcccucggaucggccccgccggggugcccug
gcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucauu
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<.......<<.....<<.<<<.....>
>>.>>......>>.........<<<<...<<<<<<....>>>>>>...>>
>>....<<<<<...<......>..>>>>>............<<<.<<<<.
.....>>>>>>>...>>>>...>>..>.>>>.<<<....<<<....<<<<
<<<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>
....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>
>>>>>.........<<<....<<<<...>>>>..>>>..>...>>.>...
..<<.<<<<<<.<<<....>>>..>>>>>>..>>......<<..<.....
......>..>>.........<<<<<((......<<<<.....<<..))>>
.......>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.
<<...<<<.<<.....<<.<.<<....>>.>.>>.<<<<<<.<.......
<<...<.......>.<<<<.......>>>>...>>......>.>>>..>>
>.......<<.<..<<<<<<<............>>>>>>>.>.>>....>
>....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>
......>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>
>>...>>>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>
...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<.....
...>>>>>>>>>.>..>>>...<<..))>>...>>.....>>>.>.>.<<
<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<
<..<<<<<..<<<.<<<<<<......<<........>>..........<<
<<<.<....<<<..........<<.<<<........>>>.>>........
>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.
.....>>>...>>.>>>....<<<...<...<<<<..<<<.....<<<..
.<<<....>>>..>>>.....>>>..>>>>..>.....<<<<<.....>>
>>>........>>>....>>>.>>>...>.>>>>>>>.....>.>>>>>.
..>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<..
..>>>>.>>>....>.........>>>.>>......<...<.<<<<<...
.......>>>>>>....>.....>>>>>.....<<<<<<<<.......>>
>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<
....<<<<<<<<.<<<..<<<<.<<...<<<<<<<<<<<<<<<..>>>>>
>>>>.>.>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8scb Structure and consequences of eRF1 glued to the ribosomal decoding center
Resolution2.5 Å
Binding residue
(original residue number in PDB)		T2 K3 K4 R5 R6 N7 N8 G9 R10 A11 K13 G14 R15 G16 H17 Q19 R28 K32 K34 K37 K38 F39 K70 V75 S76 I79 H80 V83 V84 R85 N86 R87 S88 R89 R92 K93 R95 P97 P98
Binding residue
(residue number reindexed from 1)		T1 K2 K3 R4 R5 N6 N7 G8 R9 A10 K12 G13 R14 G15 H16 Q18 R27 K31 K33 K36 K37 F38 K69 V74 S75 I78 H79 V82 V83 R84 N85 R86 S87 R88 R91 K92 R94 P96 P97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8scb, PDBe:8scb, PDBj:8scb
PDBsum8scb
PubMed38172604
UniProtG1TFE8|RS26_RABIT Small ribosomal subunit protein eS26 (Gene Name=RPS26)

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