Structure of PDB 8cqw Chain a Binding Site BS01

Receptor Information
>8cqw Chain a (length=134) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDAVTIRTRKVISNPLLARRQFVIDVLHPNRANVSKDELREKLAEIYKAE
KDAVSVFGFRTQFGGGKSTGFGLIYQSVADAKRFEPAYRLVRYGLAEKVE
KASRQQRKQKKNRDKKIFGTQRRAQKRAARRNAD
Ligand information
>8cqw Chain B (length=1741) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguacccuacuuggauaaccguggu
aauucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggaugu
auuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaau
aacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuuc
ugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacg
gguaacggggaauaaggguucgauuccggagagggagccugagaaacggc
uaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacac
ggggagguagugacaauaaauaacgauacagggcccuuuugggucuugua
auuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggca
agucuggugccagcagccgcgguaauuccagcuccaaaagcguauauuaa
aguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcuggccg
ggcguacuggacccagccgagccuuuccuucuggguagccgaaccaggac
uuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucgaauau
auuagcauggaauaauagaauaggacguuaugguucuauuuuguugguuu
cuaggaccaucguaaugauuaauagggacggucggggguaucaguauuca
guugucagaggugaaauucuuggauuuacugaagacuaacuacugcgaaa
gcauuuaccaaggacguuuucauuaaucaagaacgaaaguuaggggaucg
aagaugaucagauaccgucguagucuuaaccauaaacuaugccgacuagg
gaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaaauca
aagucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggaguggagccugcggcuuaauuugacu
caacacggggaaacucaccagguccagacacaauaaggauugacagauug
agagcucuuucuugauuuugugggugguggugcauggccguucuuaguug
guggagugauuugucugcuuaauugcgauaacgaacgagaccuuaaccua
cuaaauagugcugcuagcauuugcugguauagucacuucuuagagggacu
aucgauuucaagucgauggaaguuugaggcaauaacaggucugugaugcc
cuuagacguucugggccgcacgcgcgcuacacugacggagccagcgagua
uaagccuuggccgagaggucugggaaaucuugugaaacuccgucgugcug
gggauagagcauuguaauuguugcucuucaacgaggaauuccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauugaauggcuuagugaggccuccggauugguuua
uucuggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<............<<.....<..<<..
.....>>..>......>>........<<<<<..<<....>>..>>>>><.
..<<<<<<.......((((((.<<<....>>>..............>>>>
>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>
>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>
>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>
>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>
>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>>>>
.>>>......<<..<...........>..>>.........<<<<<((...
...<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>.
........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<.....
..............>>>>>>>>>>.....<<<<...........>>>>..
..<<<<<.<<.......<<...<.......>..<<<....>>>....>>.
.....>>.>>..>>>.........<<<..<<<<<<<<......)))))).
..>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<.<...<<<......>>>......>.>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..]]>>.
..>>.....>>>.>>>.<<<......<<<<....>>>>....>>>..]]]
].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<...
.....>>..........<<<<<......<<<<<........<<.<<<...
.....>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.
<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..
<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....
<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>>>>>
>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<......<<..
....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>......
<....<<<<<<..........>>>>>>....>.....>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<.
.<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<<...
.......>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.05 Å
Binding residue
(original residue number in PDB)
R8 T9 R10 K11 V12 R21 A33 N34 S36 K37 Y48 F58 G59 F60 T62 F64 G65 G66 Y89 R93 K102 R105 Q106 R108 K109 Q110 K112 N113 K116 K117 G120 T121 R123 R124 R128 R132
Binding residue
(residue number reindexed from 1)
R7 T8 R9 K10 V11 R20 A32 N33 S35 K36 Y47 F57 G58 F59 T61 F63 G64 G65 Y88 R92 K101 R104 Q105 R107 K108 Q109 K111 N112 K115 K116 G119 T120 R122 R123 R127 R131
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