Structure of PDB 7ut1 Chain a Binding Site BS01

Receptor Information
>7ut1 Chain a (length=264) Species: 11757 (Mouse mammary tumor virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPDWGHAPQLG
VNPRGLKPRVLWQMDVTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATK
DVLQHLAQSFAYMGIPQKIKTDNAPAYVSRSIQEFLARWKISHVTGIPYN
PQGQAIVERTHQNIKAQLNKLQKAGKYYTPHHLLAHALFVLNHVNMDNQG
HTAAERHWGPISADPKPMVMWKDLLTGSWKGPDVLITAGRGYACVFPQDA
ESPIWVPDRFIRPF
Ligand information
Receptor-Ligand Complex Structure
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PDB7ut1 B-to-A transition in target DNA during retroviral integration.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
V51 N52 P53 R54 H87 K120 G146 I147 Q152 I156 R159
Binding residue
(residue number reindexed from 1)
V51 N52 P53 R54 H87 K120 G146 I147 Q152 I156 R159
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function

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Biological Process
External links
PDB RCSB:7ut1, PDBe:7ut1, PDBj:7ut1
PDBsum7ut1
PubMed35947647
UniProtP03365|POL_MMTVB Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

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