Structure of PDB 7r7c Chain a Binding Site BS01

Receptor Information
>7r7c Chain a (length=214) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSL
KLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKL
SKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRS
TIKFQLKKVLCLAVAVGNVEMEEDVLVQQILMSVNFFVSLLKKNWQNVGS
LVVKSSMGPAFRLY
Ligand information
>7r7c Chain 1 (length=226) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcggucgaucguuucccucaggauauuuuugguaagcagaacuacccugu
ugagcuugacucuaguuugacauugugaagagacauagaggguguagaau
aagugggagcuucggcgccagugaaauaccacuaccuuuauaguuucuuu
acuauugucagguggggaguaaaguuaccacagggauaauuguggcaguc
uugcugaccgucgugagacagguuag
<<<<....>>>>.<<<....>>>...<<<<<.....>>>>>...<<<<<<
.<<<<<<..<<<<.<.<<<<<....<<<<<<<<<..<<<.<.........
.<<<<<..<<<..>>>............>>>>>..>>>>...>>>>>>>>
>.....>>>>>.>..>>>>..>>>>>.>.>>>>>>........<<<<<..
>>>>><<<<<<<....>>>.>>>>..
Receptor-Ligand Complex Structure
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PDB7r7c Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.71 Å
Binding residue
(original residue number in PDB)
R26 N27 F28 E33 Q35 K98 K101 K102 K105 K130 C164 A166 K207 S209 M210 G211 R215
Binding residue
(residue number reindexed from 1)
R23 N24 F25 E30 Q32 K95 K98 K99 K102 K127 C161 A163 K204 S206 M207 G208 R212
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7r7c, PDBe:7r7c, PDBj:7r7c
PDBsum7r7c
PubMed36482249
UniProtP0CX43|RL1A_YEAST Large ribosomal subunit protein uL1A (Gene Name=RPL1A)

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