Structure of PDB 7qiz Chain a Binding Site BS01

Receptor Information

>7qiz Chain a (length=132) Species: 4081 (Solanum lycopersicum)

MKYNPRVSSSRRKSRKAHFTAPSSVRRVLMSAPLSSELRAKYNVRSMPVR
KDDEVQVVRGTYKGREGKVVQVYRKKWVIHIERITREKVNGSTVNVGINP
SKVVVSKLRLDKDRRSLLDRKAKGRAAADKDK

Ligand information

>7qiz Chain 2 (length=3098)

gcgaccccaggucaggcgggauuacccgcugaguuuaagcauaucaauaa
gcggaggaaaagaaacuuacaaggauuccccuaguaacggcgagcgaacc
gggaacagcccagccuuagaaucgggcggcuccgucguccgaauuguagu
cuggagaagcguccucagcggcggaccgggcccaaguccccuggaagggg
gcgccggagagggugagagccccgucgugcccggacccugucgcaccacg
aggcgcugucuacgagucggguuguuugggaaugcagcccaaaucgggcg
gugaauuccguccaaggcuaaauacuggcgagagaccgauagcgaacaag
uaccgcgagggaaagaugaaaaggacuuugaaaagagagucaaagagugc
uugaaauugucgggagggaagcggaugggggccggcgaugcgccccgguc
gguguggaacggcgagccgguccgccgaucgacucggggcguggaccagc
guggauugggggggcggccaaagcccgggcucucgauacgcccguggaac
gccgucuccccgauuguggaaggcagcgcgcgccuccggcgugcuucggc
aucugcgcgcuccggacgcuggccugugggcuccccauucgacccgucuu
gaaacacggaccaaggagucugacaugugugcgagucaacgggcgaguaa
acccguaaggcguaaggaagcugauuggugggaucccccugaggggugca
ccgccgaccgaccuugaucuucugagaaggguucgagugugagcauaccu
gucgggacccgaaagauggugaacuaugccugagcggggcgaagccagag
gaaacucugguggaggcccgcagcgauacugacgugcaaaucguucgucu
gacuuggguauaggggcgaaagacuaaucgaaccgucuaguagcugguuc
ccuccgaaguuucccucaggauagcuggagcucgcgugcgaguucuaucg
gguaaagccaaugauuagaggccucggggccucgaccuauucucaaacuu
uaaauagguaggacggcgcggcugcuuuguugagccgcgccacggaauca
agagcuccaagugggccauuuuugguaagcagaacuggcgaugcgggaug
aaccggaagccggguuacggugccaaacugcgcgcuaaccuagaucccac
aaaggguguuggucgauuaagacagcagcugccgaaucaacuagccccga
aaauggauggcgcuuaagcgcgcgaccuacacccggccgucggggcaagu
gccaggccccgaugaguaggagggcgcggcggucgcugcaaaaccuuggg
cgcgagccugggcggagcggccgucggugcagaucuuggugguaguagca
aauauucaaaugagaacuuugaaggccgaagaggggaaagguuccaugug
aacggcacuugcacauggguuagucgauccuaagggucgggggaaccccg
acagauagcgcgucgcgcguacuccgaaagggaaucggguuaaaauuccu
gaaccgggacguggcgguugacggcaacguuaggaaguccggagacgucg
gcgggagccucgggaagaguuaucuuuucuguuuaacagccugcccaccc
uggaaucggcucagccggagguaggguccagcggcuggaagagcaccgca
cgugguguccggugcgcucccggcggcccuugaaaauccggaggaccgaa
ugccguccacgcccggucguacucauaaccgcaucaggucuccaagguga
acagccucuggucgauggaacaauguaggcaagggaagucggcaaaaugg
auccguaacuucgggaaaaggauuggcucugagggcuggacagccaacuc
agaacugguacggacaaggggaauccgacuguuuaauuaaaacaaagcau
ugcgauggucccaacggauguuuacgcaaugugauuucugcccagugcuc
ugaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggagua
acuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacg
cgcaugaauggauuaacgagauucccacugucccugucuacuauccagcg
aaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaagac
ccuguugagcuugacucuaguccgacuuugugaaaugacguuauuuuacu
uauuccgugaaucggaagcggguuuuuggacccaaggcucgcuucgcggg
ccgauccgggcggaagacauugucagguggggaguuuggcuggggcggca
caucuguuaaaagauaacgcagguguccuaagaugagcucaacgagaaca
gaaaucucguguggaacagaaggguaaaagcucguuugauucugauuucc
aguacgaauacgaaccgugaaagcguggccuaacgauccuuuagaccuuc
ggaauucgaagcuagaggugucagaaaaguuaccacagggauaacuggcu
uguggcagccaagcguucauagcgacguugcuuuuugauccuucgauguc
ggcucuuccuaucauugugaagcagaauucaccaaguguuggauuguuca
cccaccaauagggaacgugagcuggguuuagaccgucgugagacagguua
guuuuacccuacugaugacagugucgcaauaguaauucaaccuaguacga
gaggaaccguugauucacacaauuggccaucgcgcuugguugaaaagcca
guggcgcgaagcuaccgugugcuggauuaugacugaacgccucuaaguca
gaauccgggcuagaagcgacgcaugcgcccgccguccggccgacccgcag
uaggggccggcccccaagggcacgugucguuggcuaagucgccgcgacgg
aagcgucgcggugaccgccuugaaguacaauuuccaucgagcggcgggua
gaauccuuugcagacgacuuaaacgcgacgggguauuguaaguggcagag
uggccgccacgauccacugagauucagcccuuugucgcuccgauucgu

........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<.......<.....>......
>>>>>..[[[..<.<......<<<<<<<<<...>>>>>>>>>......>.
>...<<<<<<<<.<<<.<<<<<<<.<<<<<<.<....<<<<......>>>
>.((......<<<.....))>>>...>.>>>>>>...>>>>>>>.....>
>>>>>>>.>>>.......<<<<<<<........>>>>>>>.....(((((
..<<<<<<)))))..]]]................................
..<<....>>...............<<<<....>>>>.............
.....................<<<<<<<<<<<<......<<<<<<<<<<<
<..<<<<<.<<<<..>>>>.>>>>>....>>>>.>>>>>>>>.<.<<<<<
<..<<<<<<<<<<<<<<<.....<<<<<<<.........>>>>>.>>...
>>>>>>>>>>>>>>>.........<<<<<<<<<<...>>>..<<....>>
....>>>>>>>.....>>>>>>.>....>>>.>>>>>>>>>..<<<<...
.....>>>><<<<<<...<<<<<<<.<<<<<<..<<<..<<<<.......
.>>>>...>>>...<<....>>....<<<<<...<<<<....>>>>....
>>>>>.<<<<<<<....<<....>>....>>.>>>.>>....>>>>>>.>
>>>>>>.<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<
....>>>>>>>.....>>>...<<<<.<<.<<........>>>>>>>>..
..>>>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<
<<<<<....<.<<<....>>>.><<<<<<<<<<......<<.<<<<<<<.
....<<<....<<<..<.<<<..<<<<<..>>>>>>>>.>..>>>..>.>
>.....>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>>>.
.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<....
..>>>...<<<<<<<...<<<(((.....<<<<<<.......<.......
...<<<.<<<<<<.<<<.......<<....>>...>>>.>>>>>>>>>..
........))).>....>>>>>>.>>>...>>>>>>><<<<<<<<<....
.....>>>>>>>>>....>>>>>><.<<<<<<<<<<.......<<<.<<<
<....>>>>>>>....>>>>>>>>>>..>.....>>>>>><<.....<<.
....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<.
..<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>.
.......<<<<<.>>>>>.....>>....>>...<<<<<........>>>
>>))<<<<.<<<<<<<<...<<<....>>>...<...<<<<<<...<<<<
.<<<<<<<.<<<<<.<<<<.......>>>>.><...<<<<<.....<<<<
<<....<<<<...>>>>....>>>>>>.....>>>>>....><<<<<<<.
.>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>...>....
..>>>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<..
...>>>>..>>>>..<<<<.....<<<<<<<.<<...............<
<<<<...............>>>>><<.<<<<<<<<<<<..>>>>>..>>>
>>>.>>............<<<<<<<<<..<<<.........>>>..<<<<
<<<....<<<<....>>>>......>>>>>>>...<<..<<<..<<<<<<
...<<<.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.
......>>>>>>........<...........<<<<<.......>>>>>.
....>.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>.
...>>....<<<<<........>>>>>....[[[[[..{{{.{{......
[[[[.{{[[[[..<<<<<.<<<.<<<...<<<<<<<<<..>>>>>>>>>.
..<<<<<.....<<<<...................<<<<<<<...>>>>>
>>..>>>>..>>>>>......>>>.>>>..>>>>>...<<<.....>>>.
.<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<...
....>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<<..
.....>>>>.>>>>.<<<....>>>.>>))).......((((((..((((
.>>>>>>))))))))))..........]]]]..}}]]]].......<<.<
.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>.......<<
<<<.<<<<<<..<<<.<<<<<......>>>>>...>>>.<<<........
.>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>.
...}}..}}}.]]]]]....<<<<<<<..<<<<...<<<<<.........
........>>>>>..<<<<<...<<<<....<<<<<<<<<......>>>>
..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>
...>>>>.>>>>...>>>>>>>....<<<<<<<<<.<<.....<<.....
..<<<<<..>>>>>....>>...........<<<...<<<<<<<<<<<..
....>>>>>>>>>>>.>>>..................>>.>>>>>>>>>.
<<<<<.<.............>...<<<<<<<<<.<<<....<<<<.<..<
<<<<.>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qiz Specific features and methylation sites of a plant ribosome
• Resolution: 2.38 Å
• Binding residue (original residue number in PDB): M1 K2 Y3 N4 P5 R6 V7 S8 S9 R11 K13 S14 R15 H18 V28 L29 S31 P33 R39 R45 S46 R59 G60 T61 R86 K88 V89 N90 N99 S101 K102 R120 K121 G124 R125 D129
• Binding residue (residue number reindexed from 1): M1 K2 Y3 N4 P5 R6 V7 S8 S9 R11 K13 S14 R15 H18 V28 L29 S31 P33 R39 R45 S46 R59 G60 T61 R86 K88 V89 N90 N99 S101 K102 R120 K121 G124 R125 D129

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042273 ribosomal large subunit biogenesis

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit

External links

• PDB: RCSB:7qiz, PDBe:7qiz, PDBj:7qiz
• PDBsum: 7qiz
• PubMed: 35643637
• UniProt: A0A3Q7FBC6