Structure of PDB 7of3 Chain a Binding Site BS01

Receptor Information
>7of3 Chain a (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYSPLPDDYNCNVELALTSDGRTIVCYHPSVDIPYEHTKPIPREEGPMIE
QLSKMFFTTKHRWYPHGRYHRCRKNLNPPKDR
Ligand information
>7of3 Chain A (length=1386) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccagacaaccuuagccaaa
ccauuuacccaaauaaaguauaggcgauagaaauugaaauggcgcaauag
auauaguaccgcaagggaaagaugaaaaacaagcauaauauagcaaggac
uaaccccuauaccuucugcaaugaauuaacuagaaauaacuuugcaagga
gagccaaagcuaagacccccgaaaccagacgagcuaccuaagaacagcua
aaagagcacacccgucuauguagcaaaauagugggaagauuuauagguag
aggcgacaaaccuaccgagccuggugauagcugguuguccaagauagaau
cuuaguucaacuuuaaauuugcccacagaacccaaauccccuuguaaauu
uaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaaccu
uguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagcca
ccaauuaagaaagcguucaagcucaacacaaaaaucccaaacauauaacu
gaacuccucacacccaauuggaccaaucuaucacccuauagaagaacuaa
uguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcguca
gauacugacaauuaacagcccaauaucuacaaucaaccaacaagucauua
uuacccucacugucaacccaacacaggcaugcucauaaggaaagguuaaa
aaaaguaaaaggaacucggcaaaucuuaccccgccuguuuaccaaaaaca
ucaccucuagcaucaccaguauuagaggcaccgccuuccuuaaauaggga
uggcuccacgaggguucagcugucucuuacuuuuaaccagugaaauugac
cugcccgugagaggcgggcauaacacagcaagacgagagacccuauggag
cuuuaauuuauuaaugcaaacaaccugcauuaaaaauuucgguuggggcg
accucggagcagaacccaaccuccgagcaguacaugcuaagacuucacca
gucaaagcgaaccucaauugauccaauaacuugaccaacggaacaaguua
cccuagggaaauccuauucuagaguccauaucaacaauaggguuuacgac
cucguuggaucaggacaucccgauggugcagccgcuauuaaagguucguu
uguucaacgauuaaaguccuacgugaucugaguucagaccggaguaaucc
aggucgguuucuaucuacuuuaauuccucccuguacgaaaggacaagaga
aauaaggccuacuucacaaagcgccuucccccguaaaugauaucaucuca
acuuaguauuauacccacacacccaagaacaggguu
<<<.......<<<<.................................<..
....>...............<<.....>>...........>>.>>.....
........<<....>>...............>>>...........<<<..
.....>>>...<.<<....>>.>.<<<<<<.........<<<.<<..<<.
...>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<.
....>>>...<<<..<<<<........>>>>.>>>....>>>.>>>>>..
.<<.......>>......>.>>>>......>.>>..<<<<<<....<<<<
....>>>><<<.<<<<<<<<<<.....<<.......>>.....>>>>>>>
>>>..>>>.<<<<<<<<<<....[.>>>>>>>>>>...<<<......>>>
....<<<.<<<...<..............<....<<<.........>>>.
...>.......<<<......>>>..........................>
...>>>>>>........>>>>>>...<<<<<......>>>>>........
.>>>>>>.......<<..<<<....>>><<<<..<<<<........<<<<
<...>>>>>......<<<...<<<<.......................>>
>>.......>>>.....<<......>>.>>>>.....>>>>..<<<<...
<<<<<<<<.<<.........<......<<<<<<..<<<.........>>>
...<<<<<<.............>>>>>>....<<<.<<<<.....>>>>.
.>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.........
..<<<<<.......>>>>>.......<<..<<<.<<<...<<<<<.<<<<
<<..<<<<<.<<<<<<<<.......>>>>>>>>>>>>>..<<<<((((.>
>>><<<<<<...........>>>>>>..<<.....<<<..<<<<.....>
>>>..>>>....>>.........<<<....>>>............>>>>.
.>>>>>>>.<<<<<<<<<...<<.......>>...>>>>>>>>>]....)
))).<<<<<..<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<
.....>>>>>.....>>>>>......>>>>>.....<<<<<<<....>>>
.>>>>...>>>..>>>.>>...<<<.<<<.................>>>.
>>><<<<<...<<<....>>>.>>>>>......<<<..............
..>>>...............<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of3 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		K120 H121 Y124 P125 H126 G127 R128 Y129 H130 R133 K134 N135 P138
Binding residue
(residue number reindexed from 1)		K60 H61 Y64 P65 H66 G67 R68 Y69 H70 R73 K74 N75 P78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of3, PDBe:7of3, PDBj:7of3
PDBsum7of3
PubMed34135319
UniProtQ9Y6G3|RM42_HUMAN Large ribosomal subunit protein mL42 (Gene Name=MRPL42)

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