Structure of PDB 7o9k Chain a Binding Site BS01

Receptor Information
>7o9k Chain a (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYSPLPDDYNCNVELALTSDGRTIVCYHPSVDIPYEHTKPIPREEGPMIE
QLSKMFFTTKHRWYPHGRYHRCRKNLNPPKDR
Ligand information
>7o9k Chain A (length=1436) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccacaaccuuagcca
aaccauuuacccaaauaaaguauaggcgauagaaauugggcgcaauagau
auaguaccgcaagggaaagaugaaaaaaccaagcauaauauagcaaggac
uaaccccuauaccuucugcauaaugaauuaacuagaaauaacuuugcaag
gagagccaaagcuaagacccccgaaaccagacgagcuaccuaagaacagc
uaaaagagcacacccgucuauguagcaaaauagugggaagauuuauaggu
agaggcgacaaaccuaccgagccuggugauagcugguuguccaagauaga
aucuuaguucaacuuuaaauuugcccacagaacccucuaaauccccuugu
aaauuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaa
aaccuuguagagagaguaaaaaauuuaacccauaguaggccuaaaagcag
ccaccaauuaagaaagcguucaagcucaaaaaaaucccaaacauauaacu
gaacuccucacacccaauuggaccaaucuaucacccuauagaagaacuaa
uguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcguca
gaucacugaacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
aucacuuguuccuuaaauagggaccuguaugaauggcuccacgaggguuc
agcugucucuuacuuuuaaccagugaaauugaccugcccgugaagaggcg
ggcauaacacagcaagacgagaagacccuauggagcuuuaauuuauuaau
gcaaacaccugcauuaaaaauuucgguuggggcgaccucggagcagaacc
caaccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccuca
auugauccaauaacuugaccaacggaacaaguuacccuagggauaacagc
gcaauccuauucuagaguccauaucaacaauaggguuuacgaccucgaug
uuggaucaggacaucccgauggugcagccgcuauuaaagguucguuuguu
caacgauuaaaguccuacgugaucugaguucagaccggaguaauccaggu
cgguuucuaucuacuuucaaauuccucccuguacgaaaggacaagagaaa
uaaggccuacuucacaaagcgccuucccccguaaaugauaucaucucaac
uuaguauuauacccacacccacccaagaacaggguu
<<<.......<<<<...................................<
......>.........<.....<<.....>>....>..>>.>>.......
......<<....>>.................>>>...........<<<..
.....>>>...<.<<......>>.>.<<<<<<.........<<<.<<..<
<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<
<.....>>>...<<<..<<<<........>>>>.>>>....>>>.>>>>>
...<<.......>>......>.>>>>......>.>>..<<<<<<....<<
<<....>>>><<<.<<<<<<<<<<.....<<..........>>.....>>
>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>...<<<....
..>>>....<<<.<<<...<............<....<<<.........>
>>....>.......<<<......>>>.......................>
...>>>>>>........>>>>>>...<<<<<......>>>>>........
.>>>>>><......<<..<<<....>>><<<<..<<<<........<<<<
<.........>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<<.<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.....<<<<
..>>>>.<<<<<<.....>>>>>>..........>>>....>>.>>>>..
...>..>>.>>>>>>>>>>>>.>>.....>.....<<<<<........>>
>>>.......<<..<<<.<<.....<<<<<.<<<<<<..<<<<<.<<<<<
<<<......>>>>>>>>>>>>>..<<<<.....>>>><<<<<........
.....>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>..
.......<<<....>>>............>>>>..>>>>>>>.....<<<
<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.>....<
<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<....
.>>>>>.....>>>>>..>...>>>.>>>...<<<<<<<....>>>.>>>
>....>>..>>>.>>.....<<<.<<<.................>>>.>>
><<<<<...<<<....>>>.>>>>>......<<<................
>>>.................<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7o9k Structural basis for late maturation steps of the human mitoribosomal large subunit.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K120 H121 Y124 P125 H126 G127 R128 Y129 H130 R133 K134 N135 P138
Binding residue
(residue number reindexed from 1)		K60 H61 Y64 P65 H66 G67 R68 Y69 H70 R73 K74 N75 P78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7o9k, PDBe:7o9k, PDBj:7o9k
PDBsum7o9k
PubMed34135318
UniProtQ9Y6G3|RM42_HUMAN Large ribosomal subunit protein mL42 (Gene Name=MRPL42)

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