Structure of PDB 7a23 Chain a Binding Site BS01

Receptor Information

>7a23 Chain a (length=600) Species: 3712 (Brassica oleracea)

LIVFLPLLGSSVAGFFGRFLGSEGSAIMTTTCVSFSSILSLIAFYEVALG
ASACYLRIAPWISSEMFDASWGFLFDSLTVVMLIVVTSISSLVHLYSISY
MSEDPHSPRFMCYLSIFTFFMLMLVTGDNFLQLFLGWEGVGLASYLLIHF
WFTRLQADKAAIKAMLVNRVGDFGLALGILGCFTLFQTVDFSTIFACASV
PMRLNAISLICILLFIGAVGKSAQIGLHTWLPDAMEGPTPVSALIHAATM
VTAGVFMIARCSPLFEYSPTALIVITSAGAMTSFLAATTGILQNDLKRVI
AYSTCSQLGYMIFACGISNYSVSVFHLMNHAFFKALLFLSAGSVIHAMSD
EQDMRKMGGLASSFPLTYAMMLIGSLSLIGFPFLTGFYSKDVILELAYTK
YTISGNFAFWLGSVSVLFTSYYSFRLLFLDISRCHDAPIPMAIPLILLAL
GSNFWANSLLVLPKNEILAESEFAAPTIIKLIPILFSTLGAFVAYNVNPV
ADQFQRAFQTSTFCNRLYSFFNKRWFFDQVLNDFLVRSFLRFGYEVSFEA
LDKGAIEILGPYGISYTFRRLAERISQLQSGFVYHYAFAMLLGLTLFVTF

Ligand information

>7a23 Chain h (length=28) Species: 3712 (Brassica oleracea)

PKTWHTVTGKGLCAVMWFWILYRAKQDG

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7a23 Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): L377 P393 F394 H457
• Binding residue (residue number reindexed from 1): L366 P382 F383 H435

Enzymatic activity

• Enzyme Commision number: 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).

Gene Ontology

Molecular Function

• GO:0003954 NADH dehydrogenase activity
• GO:0008137 NADH dehydrogenase (ubiquinone) activity

Biological Process

• GO:0015990 electron transport coupled proton transport
• GO:0042773 ATP synthesis coupled electron transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0009536 plastid
• GO:0045271 respiratory chain complex I

External links

• PDB: RCSB:7a23, PDBe:7a23, PDBj:7a23
• PDBsum: 7a23
• PubMed: 33060577
• UniProt: P29388|NU5M_ARATH NADH-ubiquinone oxidoreductase chain 5 (Gene Name=ND5)