Structure of PDB 6xp5 Chain a Binding Site BS01

Receptor Information
>6xp5 Chain a (length=380) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEVIHILSKSKGLVSEAGLERLARSLELEFMWKRTLIVAGSALELLVEFS
QDVVQSVTLNFPDIVTKHAQKAGEILFNDLRLAPGQSPLTKSLARFAANF
ERLAVLDKLSILEAVADVYESLARLHAWELQKLREDPSLAGKDDEYLENL
VLCTKSGKPAMNDRGRVGLALDYEAEVASWIADNERTWSILIGCAPLRDL
SINPVRISDKWIGPNVKTSLPDGLHTGEPIIDWLDPEPTFIPATDQQQQQ
PNADTTTSKPTPNAKASHKKLDDFEAFLAKHSSHSGPISNMTPSQHQPSS
DLSIDVTLRPKLQIVFPLHATSKEEVKGKIAHEEGDQMEGVKTEGDEDGE
EKKRRRPQPGDLARALEVLEDVGKWAEFVR
Ligand information
>6xp5 Chain b (length=21) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB6xp5 Mediator structure and conformation change.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		W324 F604 E685
Binding residue
(residue number reindexed from 1)		W180 F277 E333
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0045944 positive regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xp5, PDBe:6xp5, PDBj:6xp5
PDBsum6xp5
PubMed33571424
UniProtG0SEC7

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