Structure of PDB 6j6q Chain a Binding Site BS01

Receptor Information
>6j6q Chain a (length=84) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMR
TIDQASLAQISLNGERFFGKPLKVEFSKSETKTL
Ligand information
>6j6q Chain L (length=210) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuuu
caguguaacaacuaaugaccucagaggcucauauuuguuacaauacacau
uuuuuggcacccaaaauaggacgggaagagacuuuuaaagugagacgucg
cgacccucgcaggagucguucuugacuuuuuggucgcuugauguuucucu
cuucccguuc
..................................................
...<<<<<<<<..<..<.<<<<.>>>>.>..>..>>>>>>>>........
...................<<<<<<<<<<.<<<<<.>>>>><<<<<<<<<
<<<.<<......<<<<<<....>>>>>>...>>>>>>..>>>>>>>>..>
>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6j6q Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
F65 K66 K67 R69
Binding residue
(residue number reindexed from 1)
F38 K39 K40 R42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0030620 U2 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6j6q, PDBe:6j6q, PDBj:6j6q
PDBsum6j6q
PubMed30879786
UniProtP40567|MSL1_YEAST U2 small nuclear ribonucleoprotein B'' (Gene Name=MSL1)

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