Structure of PDB 5mrf Chain ZZ Binding Site BS01

Receptor Information

>5mrf Chain ZZ (length=87) Species: 4932 (Saccharomyces cerevisiae)

PPVYRLPPLPRLKVKKPIIRQEANKCLVLMSNLLQCWSSYGHMSPKCAGL
VTELKSCTSESALGKRKSNINYHAARLYDRINGKPHD

Ligand information

>5mrf Chain aa (length=1501)

uaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacaca
ugcgaaucauacguuuauuauugagauaauaaauaugugguguaaacgug
aguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacuuaau
auuauauaaaaaauuuauauaauaaaaaggauauauauauauauauuuau
cuauagucaagccaauaaugguuuagguaguagguuuauuaagaguuaaa
ccuagccaacgauccauaaucgauaaugaaaguuagaacgaucacguuga
cucugaaauauagucaauaucuauaagauacagcagugaggaauauugga
caaugaucgaaagauugauccaguuacuuauuaggaugauauauauauau
auauaaauugauuaaaaauaaaauccauaaauaauuaaaauaaugauauu
aauuaccauauauuuauauggauauauauauauuuuaauaguccugacua
auauuugugccagcagucgcgguaacacaaagagggcgagcguuaaucau
aaugguuuaaaggauccguagaaugaauuauauauaauuuagaguuaaua
aaauuaauuaaagaauuauaauaguaaagaugaaauaauaauaauaauua
uaagacuaauauaugugaaaauauuaauuaaauauuaacugacauugagg
gauuaaaacuagaguagcgaaacggauucgauacccguguaguucuagua
guaaacuaugaauacaauuauuuauaauauauauauaaauaauaaaugaa
aaugaaaguauuccaccugaagaguacguuagcaauaaugaaacucaaaa
caauagacgguuacagacuuaagcaguggagcauguuauuuaauucgaua
auccacgacuaaccuuaccauauuuugaauauuauaauaauuauaauuau
uauauuacaggcguuacauuguugucuuuaguucgugcugcaaaguuuua
gauuaaguucauaaacgaacaaaacuccauauauauaauuuuaauuauau
auaauuuuauauuauuuaauauaaagaaaggaauuaagacaaaucauaau
gauccuuauaauauggguaauagacgugcuauaauaaaaugauaauaaaa
uuauauaaaauauauuuaauuauauuuaauuaauaauauaaaacauuuua
auuuuuaauauauuuuuuuauuauaaauaugaauuauaaucugaaauucg
auuauaugaaaaaagaauugcuaguaauacguaaauuaguauguuacggu
gaauauucuaacuguuucgcacuaaucacucaucacgcguugaaacauau
uauuaucuuauuauuuauauaauauuuuuuaauaaauauuauuaauuuau
auuuauuuauaucagaaauaauaugaauuaaugcgaaguugaaauacagu
uaccguaggggaaccugcggugggcuuauaaauaucuuaaauauucuuac
a

...<<<<..[.((((.>>>>.<<<<.<<<<<<.<<<<<<<......<<<.
<<<..<<<..<<<<<<<<<<<<..>>>>>>>>>>..>>>>>.....<<<.
.......<<<<<.<<.........<<<<<<<<.<<<<.......>>>>..
.<<<<<<<<<...>>>>>>>>>......<<<<<<<<<..>>>>>>>>>.>
>>>>>>>....>>>>>>><<<....<<<..<<<<<<<<........>>>>
>>>>>>>......>>>..<<<<.<<<<....>>>>...>>>>.>>><<<<
<<.........>>>>>><<<<.....>>>>..>>>>>>.........<<<
....<<<<....>>>>..>>>...>.>>>>>>.<<<<..<<<<<<....>
>>>>>..<<......>>.....>>>>..<<<<<<<<..............
>>>>><<<<<<<..>>>>>>><<<<<..>>>>>>>>....<<<<<(((..
...<<<<.....<<.)))>>.......>>>>.>>>>>.>>>>>>>>>>..
...<<<((.....<<<<...<.<<.<<<<<<..>>>>>>...<<<<<<<<
...<<<<<<<<<<..<<<<<<<........................>>>>
>>>..>>.......<<....>>.>>>>>>>>.>>>>>>>>...>>>...>
>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>.
.........<<<<<<.<<<<<<<<<<.<..>..>>>>>>>>>>..<<..)
)>>....>>>>>>.>>>.<<.......<<<<....>>>>.....>>..))
)).]<<.<<...<<<<.....<<<<<<..<<<<<<<<<<......<<...
.....>>..........<<<<<<<.....<<.<<<<<<<<<<..>>>>>>
>>>>.>>.<<<.<<<..<<<<<<<<<....<<<<<<<<<....>>>....
<<......>>....>>>>>>.....<<<.<<<<<<<<........>>>>>
>>>..<<<<<<<<<..>>>>>>>>>....>>>.....>>>.>>>...>>>
>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<........<
<<..<<..<<<<<<......>>>>>>..>>....>>>......>>>>>>.
.....<<<<<........>>>>>......<....<<<<<<<........>
>>>>>>....>.....>>>>>>....<<.<<<<<.........>>>>>>>
...........>>>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<
<<<<.<<<...<<<..<<<.<<<<<...<<<<<<<...>>>>>>>...>>
>>>>>>..>>>..>>>>>>>>>>>>..>>>>>>>>..>.>>>..>.....
<<<<<<<<<....>>>>>>>>>............................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5mrf The structure of the yeast mitochondrial ribosome.
• Resolution: 4.97 Å
• Binding residue (original residue number in PDB): R9 P12 L13 P14 R15 V18 K19 K20 P21 I22 R24 K75 I78 N79 Y80 P93
• Binding residue (residue number reindexed from 1): R5 P8 L9 P10 R11 V14 K15 K16 P17 I18 R20 K67 I70 N71 Y72 P85

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005759 mitochondrial matrix
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5mrf, PDBe:5mrf, PDBj:5mrf
• PDBsum: 5mrf
• PubMed: 28154081
• UniProt: O75012|MRP10_YEAST Small ribosomal subunit protein mS37 (Gene Name=MRP10)