Structure of PDB 8y6o Chain Z Binding Site BS01

Receptor Information
>8y6o Chain Z (length=210) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAE
LAERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAV
EREQEIDRWRVKCVQEVEEKKREQELKAAADGVLSEVRKKQADTKRMVDI
LRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLRKLIKKRSELYEA
EERALRVMLE
Ligand information
>8y6o Chain P (length=124) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaaagggcuucugucgugaguggcacacguagggcaacauugcucugcg
ugcggaaucgacaucaagagauuucggaagcauaauuuuuugguauuugg
gcagcuggugauucccggcgcccu
.......<<<<.<<<<......>>>><<<<<<<<<<<<..>>>>>>>>>>
>><<<<<<<..........>>>>>>>.>>>>.................<<
<<.<<<<<.<<.>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB8y6o Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome
Resolution3.38 Å
Binding residue
(original residue number in PDB)		S170 L171 R175 R238 V242 R244 R245 R246 R248 R250 R252
Binding residue
(residue number reindexed from 1)		S2 L3 R7 R70 V74 R76 R77 R78 R80 R82 R84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006915 apoptotic process
GO:0008380 RNA splicing
GO:0051384 response to glucocorticoid
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005689 U12-type spliceosomal complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8y6o, PDBe:8y6o, PDBj:8y6o
PDBsum8y6o
PubMed38484052
UniProtQ8N8D1|PDCD7_HUMAN Programmed cell death protein 7 (Gene Name=PDCD7)

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