Structure of PDB 8urw Chain Z Binding Site BS01

Receptor Information
>8urw Chain Z (length=1235) Species: 32046 (Synechococcus elongatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EAKSAPIFRNRVIDKKQLKKLIGWTFAHYGTAKTAVVADDLKALGFRYAT
RAGVSISIDDLKVPGSKAELLESAEKRIQETEDRYTRGEITEVERFQKVI
DTWANTNDELTDRVVKNFRESDPLNSVYMMAFSGARGNISQVRQLVGMRG
LMANPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGY
LTRRLVDVSQDVIIHEVDCGTSRGLFVEAMTDGDRILIPISQRLLGRVTA
EAVLDPSTDEVLAEAGQDINEDLANRIEKAGIKKVKVRSPLTCEAARSVC
QKCYGWSLAHAQMVDMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGET
ARLLRAPVAGTIKLGKKARTRPYRTRHGEEALLAEANFDLVLEGKGRKET
FAILQGSTIFVQDGDKVAAEAILAEVPVSGRTKRTVEKATKDVATDLAGE
IRFQDIVPEEKTDRQGNTTRIAQRGGLLWVLAGDVYNLLPGAEPTVKNGD
RVEVGDVLAETKLTTERGGTVRMGEDNGSSTHREVEIITASVVLDTATVK
AEASQGREHYVIETKGGQRFNLLAAPGTKVTTGHVVAELIDSRYRTQTGG
LLKYSGVEISKKGRAKAKQGYEVTKGGTLLWIPEETHEVNKDISLLNVED
GQLVEAGTEVVKDIFCQTTGIVSVTQNNDILREIVIKPGDVHVLDDPDTA
AKYDEGRLVNAGEEVFPGLTAEQLVWAEAVDGTDGPLLLLRPVQELVIPD
EPPVPSQDSSQESSSRSIRLRAVQRLQFQDGERIKSVEGVDLLRTQLVLE
SEEGSSQLSADIELLPDSKDPETLRLQLVIIEPVVIRRDVASDTTHGSTH
TELRVKDGQKVKPGAVIACTQIQCKEAGVVRGIQEGSEAVRRLLVERERD
CVTLDLDVTAATQLQPGSLIVAGTQLVDGIIAPESGEVRAIAPGQLQLRI
ARPYRVSQGAVLHVEDKGLVQRGDNLVLLVFERAKTGDIIQGLPRIEELL
EARKPKEACILARRPGVAHINYSDDDAIDIQVIEADGTQADYPVGPGQPL
IISDGETVDAGQALTDGPANPHDLLEIYYDYFREQLGEDYEAALESLRRV
QALLVNEVQSVYQSQGIDISDKHIEVIVRQMTSKVRIDDGGDTIMLPGEL
HELREVYNSNNTMALTGMAPAQFTPVLLGITKASLNTNSFISAASFQETT
RVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFK
Ligand information
>8urw Chain T (length=40) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggcagtcgccgtgtacctctcctagagcagcatgcgccc
Receptor-Ligand Complex Structure
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PDB8urw Cryo-EM structure of a cyanobacterial RNAP elongation complex with NusG and CTP.
Resolution2.79 Å
Binding residue
(original residue number in PDB)
A198 Y202 R466 Q1199
Binding residue
(residue number reindexed from 1)
A196 Y200 R464 Q1197
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8urw, PDBe:8urw, PDBj:8urw
PDBsum8urw
PubMed38354263
UniProtQ31N15|RPOC2_SYNE7 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC2)

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