Structure of PDB 8ese Chain Z Binding Site BS01

Receptor Information
>8ese Chain Z (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYL
KTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASL
ALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPS
FVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ese Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		L25 L152 Y163 Y165 V174 E175 R176
Binding residue
(residue number reindexed from 1)		L26 L153 Y164 Y166 V175 E176 R177
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0010506 regulation of autophagy
GO:0015031 protein transport
GO:0032456 endocytic recycling
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0030904 retromer complex
GO:0030906 retromer, cargo-selective complex
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ese, PDBe:8ese, PDBj:8ese
PDBsum8ese
PubMed37172566
UniProtQ9UBQ0|VPS29_HUMAN Vacuolar protein sorting-associated protein 29 (Gene Name=VPS29)

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