Structure of PDB 8c99 Chain Z Binding Site BS01

Receptor Information
>8c99 Chain Z (length=57) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAV
SFMVKVE
Ligand information
>8c99 Chain A (length=945) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcua
aucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauu
uccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauc
cauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccga
ggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggag
cagcccagagccugaaucaguguguguguuaguggaagcgucuggaaagg
cgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugag
cucgaugaguagggcgggacacgugguauccugucugaauaugggggauc
cuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugag
ggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaacc
guguacguacaagcagugggagcacgcuuaggcgugugacugcggucagc
gacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaac
cgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggug
aucaccgggagauagcugguucuccccgaaagcuauuuagguagcgccuc
gugaauucaucuccgggggagaauguuaucacgggagacacacggcgggu
gcuaacguccgucgugaagagggaaacaacccagaccgccagcuaagguc
ccaaagucaugguuaagggggcuaaaccaugcaccgaagcugcggcagcg
acgcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggug
ugcugugaggcaugcuggagguaucagaagugcgaaugcugacau
.<<<<<<<<<<<....<<<..<<<<<<<<<<<<<......<<<<<<.[..
(((.>>>.....<<<<<<<..<<<)))..].>>>......>>>>>>>...
>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.....
....>>>>>>>>>.>>...<<<<<<.....<<....>>......>>>>>.
>.........<<....>>...<<<<<.....<<.....>>....>>>>>.
..<<<..<<<<......<<<<<<<<<<<<<.<<<...<<<<<......>>
>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>
>>>........<.<.<<<<.........>>>>.>.>......<<<<<..>
>>>>..>>>......>>.>>>>>>>.>>...............<<....>
>....>>.........<<<<.....>>>>.............>....>>>
>>>>>>>>.......<<<<..<<<<<......>>>>>..>>>>.<<<<<<
....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>
>...<........>.......>>>>>>>>>>>>>..<<.<..<<<<<<<.
...>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<
<<<<...<<<<<<<...>>>>.>>>...>>>>>>>.>...<<<<<<<<<.
.......>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(
((.....<<<<<<....))).....>>>>>>.>>>...>>>>>>><<<<<
<<<<....>>>>>>>>>....>>>>>><<<<<<<...<<<......<<<<
<<<<....>>>>>>>>...>>>..>>>>>.>>.....>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c99 Cryo-EM captures early ribosome assembly in action.
Resolution3.29 Å
Binding residue
(original residue number in PDB)		R10 S11 I13 P17 T22 G25 R29 I31 A42 G45 M46
Binding residue
(residue number reindexed from 1)		R10 S11 I13 P17 T22 G25 R29 I31 A42 G45 M46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c99, PDBe:8c99, PDBj:8c99
PDBsum8c99
PubMed36797249
UniProtP0AG51|RL30_ECOLI Large ribosomal subunit protein uL30 (Gene Name=rpmD)

[Back to BioLiP]