Structure of PDB 8c01 Chain Z Binding Site BS01

Receptor Information
>8c01 Chain Z (length=127) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAA
MLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGL
RIGRIEDVTPVPSDSTRKKGGRRGRRL
Ligand information
>8c01 Chain 2 (length=1545) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguuacaugguauaacugugguaauucua
gagcuaauacaugcuuaaaaucucgaagagauguauuuauuagauaaaaa
uugaugauucauaauaacuuuucgaaucgcauggccgcuggcgaugguuc
auucaaauuucugcccuaucaacuuucgaugguaggauaguggccuacca
ugguuucaacggguaacggggaauaaggguucgauuccggagagggagcc
ugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuaccc
aauccuaauucagggagguagugacaauaaauaacgauacagguuguauu
ggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggcaagu
cuggugccagcagccgcgguaauuccagcuccaauagcguauauuaaagu
uguugcaguuaaaaagcucguaguugaacuuugggcccgguuggccaacg
gggccuuuuuuacuuugaaaaaauuagaguguucaaagcaggcgugcucg
aauauauuagcauggaauaauagaauaggacguuugguucuauuuuuuuc
uaggaccaucguaaugauuaauagggacggucgggggcaucaguauucaa
uugucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaag
cauuugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucga
agaugaucagauaccgucguagucuuaaccauaaacuaugccgacuaggg
aucgggugguguuuuuaaugacccacucggcaccuuacgagaaaucaaag
ucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaaggaau
ugacagggcaccaccaggaguggagccugcggcuuaauuuggaaacucac
cagguccacacaauaagauugacagauugagagcucuuucuugauuuugu
ggguggugggccgguugguggagugauuugucugcuuaauugcgauaacg
aacgaccuuaaccacuaauaguggugcuagcauuugcugguuccacuucu
uagagggacuaggaaggaggggucccuuagacguucugggccgcacgcgc
gcuacacugacggagccagcgagucuaaccuuggccgagaggucuuggua
aucuugugaaacuccgucgugcuggggauagagcauuguaauuauugcuc
uucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuac
gucccugcccuguaccuaguaccgauugaauggcuuagugaggccucagg
aucugcuuagagucagagcggagaauuuggacaaacuuggucauuuagag
gaacuaagguuuccguaggugaaccugcggaaggaucauuaaaga
..<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<.......>>...>>.>>......<<......
..<<<..<<..<<....<<<........<<......<<.<<.......>>
.>>......>>........<<<<<...>>>>><.<.<<<<<<......((
...........>>>>>>.>...>...<<<<..<<<.>>>.>>>>....>>
>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>
>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.
.........>>>.>>.<.<<<..>>>.>...>>>>>>.........<<<.
...<<<.....>>>..>>>..>....>.>.....<<<<<<<<.>>>>>>>
>......<<..<...........>..>>.........<<<<<((....<.
<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>>>>>>....
.....<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<..>>>>.
>>>>>>...<<<<<.<<.......<<...<.......>..<<<..>>>..
..>>......>>.>>..>>>.........<<<..<<<<<<<<.....)).
>>>>>>>>.>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<
<.<...<<<..(...>>>......>.>>>>>>..>>.......<<....>
>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<..
.<<<<..)......>>>>...>>>>>>>>..........<<<.<<.<<<.
.<<<<<<<<.<<<......>>>>>>>>>>>..>>>...<<..]]>>...>
>.....>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}
....<<<<<<..<<.<<<<<<..<<<.<<<<<<................<
<<<<.<..<<<<<.......<<.<<<........>>>.>>......>>>>
>......<<<<<.<<<.<<<<......>>...<<<......>>>...>>.
>>>..<<<<..<<.<<<..<<<<<.<<<<<<<..>>>>>>>.>>>>>...
>>>.>>..........>>>>>>>>>.......>.>>>>>...>>.>>>>.
>>>.....<<<<<<<......<<.....<<..<<<<....>>>>..>>..
..>>.......>>>>>>>......<....<<<<<<..........>>>>>
>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>......
>>...>>>>>>.....<<<<.<<....<<<<<<<<.<<<..<.<<..<..
.<<<<<<<.......>>>>>>>...>..>>.>..>>>.>>>>>>>>...>
>.>>>>....<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c01 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N24 D25 F27 K36 T38 R41 G45 D51 P122 S123 D124 T126 R127 R132
Binding residue
(residue number reindexed from 1)		N14 D15 F17 K26 T28 R31 G35 D41 P112 S113 D114 T116 R117 R122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c01, PDBe:8c01, PDBj:8c01
PDBsum8c01
PubMed36996028
UniProtP06367|RS14A_YEAST Small ribosomal subunit protein uS11A (Gene Name=RPS14A)

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