Structure of PDB 7q5b Chain Z Binding Site BS01

Receptor Information
>7q5b Chain Z (length=289) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGR
RSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHI
TELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRP
AGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKL
SVQKFRENDVEDGEARPPSFVKNRKKERKIPRNLHLLPTTDTYLSKVSDD
PDNLEDVDDEELNAHLLNEEASKLKERIWIGLNADFLLE
Ligand information
>7q5b Chain R (length=56) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagcccgtaatacaacagattttttctcttagttttaaatttttatattt
cgtcga
Receptor-Ligand Complex Structure
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PDB7q5b Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Resolution3.98 Å
Binding residue
(original residue number in PDB)		V117 Q118 R120 R218 R219 V250 A251 E253 T254 S289 N293
Binding residue
(residue number reindexed from 1)		V47 Q48 R50 R148 R149 V180 A181 E183 T184 S219 N223
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000994 RNA polymerase III core binding
GO:0000995 RNA polymerase III general transcription initiation factor activity
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001156 TFIIIC-class transcription factor complex binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001112 DNA-templated transcription open complex formation
GO:0006352 DNA-templated transcription initiation
GO:0006359 regulation of transcription by RNA polymerase III
GO:0006383 transcription by RNA polymerase III
GO:0070897 transcription preinitiation complex assembly
GO:0070898 RNA polymerase III preinitiation complex assembly
Cellular Component
GO:0000126 transcription factor TFIIIB complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0097550 transcription preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7q5b, PDBe:7q5b, PDBj:7q5b
PDBsum7q5b
PubMed34848735
UniProtP29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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