Structure of PDB 7of7 Chain Z Binding Site BS01

Receptor Information
>7of7 Chain Z (length=115) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFTRSRIPEKVFQASPEDHEKYGGDPQNPHKLHIVTRIKSTRRRPYWEKD
IIKMLGLEKAHTPQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPAEENM
SNTCLKSTGELVVQW
Ligand information
>7of7 Chain A (length=1376) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccaaaccuuagccaaacca
uuuacauaaaguauaggcgauagaaauugauggcgcaauagauauaguac
cgcaagggaaagaaagcauaauauagcaaggacuaaccccuauaccuucu
gcauaaugaauuaacuagaaauaacuuugcaaggagagccaaagcuaaga
cccccgaaaccagacgagcuaccuaagaacagcuaaaagagcacacccgu
cuauguagcaaaauagugggaagauuuauagguagaggcgacaaaccuac
cgagccuggugauagcugguuguccaagaugaaucuuaguucaacuuuaa
auuugcccacagaacccaaauccccuuguaaauuuaacuguuaguccaaa
gaggaacagcucuuuggacacuaggaaaaaaccuuguagagagaguaaaa
aauuuaacacccauaguaggccuaaaagcagccaccaauuaagaaagcgu
ucaagcucaacacaaaaaucccaaacauauaacugaacuccucacaccca
auuggaccaaucuaucacccuauagaagaacuaauguuaguauaaguaac
augaaaacauucuccuccgcauaagccugcgucagcugacaauuaacagc
ccaauaucuacaaucaaccaacaagucuuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccuuccuuaaauagggauggcuccacgaggguucagc
ugucucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggc
auaacacagcaagacgagaagacccuauggagcuuuaauuuauuaaugca
aacaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccuuugau
ccaauaacuugaccaacggaacaaguuacccuagggauaacagcgcaauc
cuauucuagaguccauaucaacaauaggguuuacgaccucgauguuggau
caggacaucccgauggugcagccgcuauuaaagguucguuuguucaacga
uuaaaguccuacgugaucugaguucagaccggaguaauccaggucgguuu
cuaucuacuuuaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacacccaagaacaggguu
<<<.......<<<<..............................<.....
.>...........<<.....>>.........>>.>>.............<
<....>>.......>>>...........<<<.......>>>...<.<...
.....>.>.<<<<<<.........<<<.<<..<<....>>...>>.>>>.
..<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>...<<<<.
<<<<........>>>>>>>>....>>>.>>>>>...<<.......>>...
...>.>>>>......>.>>..<<<<<<...<<<<....>>>><<<.<<<<
<<<<<<.....<<.......>>.....>>>>>>>>>>..>>>.<<<<<<<
<<<......>>>>>>>>>>...<<<......>>>....<<<.<<<...<.
.............<....<<<.........>>>....>.......<<<..
....>>>..........................>...>>>>>>.......
.>>>>>>...<<<<<......>>>>>.........>>>>>>.......<<
..<<<....>>><<<<..<<<<........<<<<..>>>>......<<<.
..<<<<......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
<......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<.<<<<.....>>>>..>>>....>>.>>>>.....
>..>>.>>>>>>>>>>>>.>>...........<<<<<........>>>>>
.......<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<
......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
.<<<....>>>............>>>>..>>>>>>.......<<<...<<
<<<<<...<<.......>>...>>>>>>>....>>.>......<<<<<<.
<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>
.....>>>>>..>...>>>.>>>...<<<<<<<....>>>.>>>>....>
>..>>>.>>...<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<.<............>.>>>.....
..........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of7 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K35 F36 T37 R38 S39 R40 R71 K73 S74 R76 R77 R78 P79 Y80 K83 M88 K93 A94 K101 S105 V106 K109
Binding residue
(residue number reindexed from 1)		K1 F2 T3 R4 S5 R6 R37 K39 S40 R42 R43 R44 P45 Y46 K49 M54 K59 A60 K67 S71 V72 K75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of7, PDBe:7of7, PDBj:7of7
PDBsum7of7
PubMed34135319
UniProtQ8TCC3|RM30_HUMAN Large ribosomal subunit protein uL30m (Gene Name=MRPL30)

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