Structure of PDB 6j6n Chain Z Binding Site BS01

Receptor Information
>6j6n Chain Z (length=447) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEDIKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIIC
KNVVDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFN
RKDYVSCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKI
CGWKLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKS
GSQGLFILDPTSYTVHTHSYIVSDEDEANKELGNFEKCENQIYDMTSTND
VEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKKSVVDIIIKSSLQEST
FSKFYSILSERMITFHRSWQTAYNETFEQNYTQDIEDYETDQLRILGKFW
GHLISYEFLPMDCLKIIKLTEEESCPQGRIFIKFLFQELVNELGLDELQL
RLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLLTEDMRSRLTIIQ
Ligand information
>6j6n Chain J (length=27) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SYNGIGLKSAKGSSTSGHVQRSLASNN
Receptor-Ligand Complex Structure
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PDB6j6n Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Resolution3.86 Å
Binding residue
(original residue number in PDB)		H310 L313 R349
Binding residue
(residue number reindexed from 1)		H272 L275 R311
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6n, PDBe:6j6n, PDBj:6j6n
PDBsum6j6n
PubMed30879786
UniProtP53333|CWC22_YEAST Pre-mRNA-splicing factor CWC22 (Gene Name=CWC22)

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