Structure of PDB 5xyi Chain Z Binding Site BS01

Receptor Information
>5xyi Chain Z (length=73) Species: 5722 (Trichomonas vaginalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKREWAVIITPEQAADMVKSVPKNKVISAGKLAERYKISLTCARKALEAL
TAEGKIVPVINGHDLKCYGPHPD
Ligand information
>5xyi Chain 2 (length=1490) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acuugguugauccugccaaggaagcacacuuaggucauagauuaagccau
gcaaguguuaguaacugcgaauagcucauuaauacgcucagaaucuauuu
ggcggggauagcagcagcaacucuggugcuaauacaugcuguuucuccag
augugaauuauggaggaaaaguugaccucgaggcacgccauucgacugag
ugaccuaucagcuuguacuuagggucuuuaccuagguaggcuaucacggg
uaacgggcgguuaccgucggacugccggagaaggcgccugagagauagcg
acuauauccacggguagcagcaggcgcgaaacuuucccacucgagacuuu
cggaggagguaaugaccaguuccauugguuacguggauagggguacgguu
uuccaccguaccgacuagcagagggcagucuggugccagcagcugcggua
auuccagcucugcgaguuugcucccauauuguugcaguuaaaacgcccgu
agucugaauuggccagcaauggucguacguauacguucacugugaacaau
caggacgcuuagaguauggccacaugaaugacucagcgcaguaugaaguc
uuuguuaaaacaagcucaaugagagccaucggggguagaucuaucucaug
acgagugguggaauacuuugacucaugagagagaagcugaggcgaaggcg
ucuaccuagaggguuucugucgaucaagggcgagaguaggaguauccaac
aggauuagagacccugguaguuccuaccuuaaacgaugccgacaggaguu
ugucauuuguuaauggcagaaucuuuggagaaaucauaguucuugggcuc
ugggggaaauacgaccgcaaggcugaaacuugaaggaauugacggaaggg
cacaccagggguggagccuguggcuuaauuugaaucaacacggggaaacu
acccaggaccagauguuuaugacugacaggcuucgggucuuucaggauau
uguuuuugguggugcauggccguugguggugcguggguugaccuguccgu
ugauucagcuaacgagcgagauuaucgccaauuauuuacuuugccgaagu
ccuucgguuaaaguucuaauugggacucccugcguagcagguggaagagg
guagcaauaacagguccgugaugcccuuuagaugcucugggcugcacgcg
ugcuacaauguuaggacaauaggagcgagccugagagggugcgcuacucu
uauaaucccuaacguaguugggauugacguuuguaaucagcgucaugaac
caggaaucccuuguaaaugugugucaacaacgcacguugaauacgucccu
gcccuuuguacacaccgcccgucgcuccuaccgauuggaugacucgguga
aaucaccggauggaaagugauuaaaucacguuaucuagaggaaggagaag
ucguaacaagguaacgguaggugaaccugccguuggauca
..<<<<<.[.((((>>>>><<.<<<<.<<...<<<<<<<......<<<.<
<<..<<....<<.>>.>>......<<........<<<<<<...<<....<
<<<<..<...<<<.<<.......>>.>>>.....>......<<<<<<<<.
..<.....>.>>>>>>>>.......<<<..>>>..>>>>>...>>.>>>>
>>.<<<....<<<..<<<<<<<<.......>>>>>>>>>>>......>>>
...<<<.<<<<....>>>>.....>>>.>>.<<.<<<..........>>>
.>>.<<<<....>>>>...>>>>>>.........<<<....<<<<...>>
>>..>>>..>>.>>>>>...<<<<.<<....>>>>>>....<<<<<<<<.
....>>>>>>>>.....<<<<<((...<.<<<<.....<<..))>>....
...>>>>>>>>>>..>>.>>>>.>>.........<<<((.....<<<<..
.<<<.<<...<<<<......>>>>....<<..>>.<<<<<<<<<.....<
<<..<<.......>><<<....>>>...>>>.....>>>>>..>>>>...
...<<....>>....>>....<<<<<<.<...<<<<<<<<<..<<<<<<<
<...<<<......>>>......>>>>>>>>..>>.......<<....>>.
>>>>>>>...>>>>.>>>...>>>...>>>>..<.<<<<<<<...<...<
<<<.<.....>.>>>>...>>>>>>>>..>.......<<<.<<.<<<.<<
<<<<<<<....>>>>>>>>>.>>>...<<..))>>...>>.....>>>.>
>>.<<<......<.<<....>>.>....>>>..)))).]<<<<<.<<<<<
<<.<<..<<<<<..<<<.<<<<<<......<<........>>........
.<<<<<<...............<<<<.<<<.......>>>.>>>>.....
.......<<.<<<..<<.<<<<<<....<<.<<<<<<....>>>..<.<.
.....>.>...>>>.>>....<<<<<.<<<<<<<...<<<<<<<<<<<..
..>>>>>>.>>>>>..>>>>>>>.....<<<<<...>>>>>........>
>>>>....>>>.>>>.....>>>>>>>........>>>>>>..>>.>>>>
.>>>.....<<<<<<.....<<<.<<..<<<<....>>>>..>>....>>
>......>>>>>>...........<<<<<<<.......>>>>>>>.....
.....>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>
>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<<<<<<..<<<..
<<<<<<..........>>>>>>..>>>..>>>>>>>...>>.>>>>>..>
.>>...>.....<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xyi Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Resolution3.35 Å
Binding residue
(original residue number in PDB)		W22 L57 T58 R61 K62 H80
Binding residue
(residue number reindexed from 1)		W5 L40 T41 R44 K45 H63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5xyi, PDBe:5xyi, PDBj:5xyi
PDBsum5xyi
PubMed28809395
UniProtA2ER97

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