Structure of PDB 3qe9 Chain Z Binding Site BS01
Receptor Information
>3qe9 Chain Z (length=344) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEP
TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLL
KGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEA
DAQLAYLNKAGIVQAIITEDSALLAFGCKKVILKMDQFGNGLEIDQARLG
MCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIV
KVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAY
EDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDT
Ligand information
>3qe9 Chain A (length=12) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
cgctagtcgaca
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3qe9
Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family.
Resolution
2.51 Å
Binding residue
(original residue number in PDB)
K37 I40 T120 R121 G232 G234 A236 K237
Binding residue
(residue number reindexed from 1)
K36 I39 T119 R120 G231 G233 A235 K236
Enzymatic activity
Enzyme Commision number
3.1.-.-
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003824
catalytic activity
GO:0004518
nuclease activity
GO:0016788
hydrolase activity, acting on ester bonds
GO:0035312
5'-3' DNA exonuclease activity
GO:0046872
metal ion binding
View graph for
Molecular Function
External links
PDB
RCSB:3qe9
,
PDBe:3qe9
,
PDBj:3qe9
PDBsum
3qe9
PubMed
21496642
UniProt
Q9UQ84
|EXO1_HUMAN Exonuclease 1 (Gene Name=EXO1)
[
Back to BioLiP
]