Structure of PDB 1p8k Chain Z Binding Site BS01

Receptor Information
>1p8k Chain Z (length=254) Species: 162425 (Aspergillus nidulans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSDLTYAYLVGLFEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKI
LGIGIVSFRKRNEIEMVALRIRDKNHLKSFILPIFEKYPMFSNKQYDYLR
FRNALLSGIISLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGC
FSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSK
LKVTSVRSVENIIKFLQNAPVKLLGNKKLQYLLWLKQLRKISRYSEKIKI
PSNY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1p8k Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K24 Y27 I55 R59 R61 R70 R72 K74 E148 Q171 R172
Binding residue
(residue number reindexed from 1)		K24 Y27 I55 R59 R61 R70 R72 K74 E148 Q171 R172
Binding affinityPDBbind-CN: Kd=11nM
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1p8k, PDBe:1p8k, PDBj:1p8k
PDBsum1p8k
PubMed14633971
UniProtP03880|ANI1_EMEND Intron-encoded DNA endonuclease I-AniI (Gene Name=I-AniI)

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