Structure of PDB 1ml5 Chain Z Binding Site BS01

Receptor Information
>1ml5 Chain Z (length=362) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERA
QALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAEL
DALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYL
RWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVR
KSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQH
VNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKK
NAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSL
DQFIEASLKAGL
Ligand information
>1ml5 Chain B (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcggauuuagcucaguugggagagcgccagacugaagaucuggagguccu
guguucgauccacagaauucgcacca
<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB1ml5 Structure of the Escherichia coli ribosomal termination complex with release factor 2
Resolution14.0 Å
Binding residue
(original residue number in PDB)		Q252 H253 V254 N255 R256 E258 R278
Binding residue
(residue number reindexed from 1)		Q249 H250 V251 N252 R253 E255 R275
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ml5, PDBe:1ml5, PDBj:1ml5
PDBsum1ml5
PubMed12511961
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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