Structure of PDB 6ywx Chain YY Binding Site BS01

Receptor Information

>6ywx Chain YY (length=99) Species: 367110 (Neurospora crassa OR74A)

SVPRARLLQLVKARCELFSTTFNPEGIRTGNKILRQRLKGPALATYYPRK
NVGIRELQKEFGTLGLEVDDEVDDDRLEHLAALRARDKGAPKKKRTAPS

Ligand information

>6ywx Chain aa (length=1435)

auagaugaguuuggugauggcucugauugaacacuguccaaauacuugac
acaugcuaaucgaacguuuaauuuuggcucuuaauuaaaagugguguaca
ggugaguauaauauuuuuucgcuuaacuuaaagugaaggcaaauccuuca
uauugcaaaaggauaucuauauccgcuuuaagaggaugagaaaaguuuca
gagauagguaguuguuaaggucauggcuuaacaagccaauaauucucuua
gucgaagcugaaaaggcugaucgaccacauugggaaugaaaaaaucccaa
ggcaaauagguacagcagugaggaaucuuggucaaugggcccacgccuga
acugguaacuuggaggaaugagacgucgauuuaucgaguaaaauucugua
uacauauugauaaugacaauauguacauuugucuugacuaauuacgugcc
agcagucgcggcaauacguaagagacuaguguuaaucaucauaaauaggu
uuaaaggguacucagacggaaaaauucgcccaaauauaggggacaauuuu
ucuagaguuuuauguaagaaggucguacucuagaguggagagauaaaauu
cugugauaccuaggggacggguaaaggcgaaggcaaucuuuuauguaaaa
acugacgucgaaggacgaaggcaaagggaacaaaaaggauuagauacccc
aguagucuuugcagacaauuaugaaugccauagguuagauuuuuaauuua
gucuauaaaugaaaguguaagcauuucaccucaagaguaaggcggcaacg
caggaacugaaaucacuagaccguuucugacaccagcaaugaaguauguu
auuuaauucggugacccacgaaaaaccuuaccacaauuugaauauuaauu
auuaauacaaguguugcacggcugucuucaguugauguugcgaaacugug
guucguuccauggaauuaacguaaacccuugcuuuauuuguaaauauuau
aaagcaguucaccuuuauauaggaaaugauaaaagggaucaagacaaguc
aucauggccuaaauauugugggcuauagacgugccacauuuuccuaaaca
aagagaugcaaaaaugugaauuuuagcuaaucucaaaaaauaggauaaaa
auauacaaggauuguagucugaaauucgacugcaugaauaagaaauugcu
aguaaucgugaaucaccaugacacggugaauauucccucggauugguacu
aaccacucgucacaugcugaaaggagugcgugcaauaaguuugcuuuucu
guuauaaguaaguagacauauagguuuagauguuauaauaggauccuucg
uaugcgcggcucugauuaguguuaagucgaaauacgguucguguagugga
aguugcacgggacuuaucaauguugaacaauacga

......((((..<<<<<<.))))<<<<<.<<<<<..<<<<<.<<.....<
<<.<<<..<<<..<<.<<<<<<<..<<.>>..>>>>>>>.>>>>>.....
.<<.........<<<<<<<..<<...<<<<<<<<<<<<<.....>>>>>.
..........<<<<<<..>>>>>>>>>>>>>>.>>...(>>>>>>>...<
<<<<..<<<..<<<<<<<<....)..>>>>>>>>>>>......>>>>>..
<<<<.<<<<.....>>>>...>>>>.>>.<<<<<...........>>>>>
.<<......>>...>>>>>>.........<<<....<<<<....>>>>..
>>>..>>..>>>>>.<<<<......<<<<....>>>>.....>>>>....
<<<<<<<<<.......>>>>>>>>>.....<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>>.........<<<
((.....<<..<..<<<.<<<<<<<<.<<<<.......>>>..>>>>>>>
>>...<<<<<......<<<<<<<.<..<<<<<<.<<<..<<<......>>
>.....>>>>>>>>>..>........<<....>>.>>>>>>>......>>
>>>...>>>...>.>>....<<<<<<...<<.....<<.........>>.
....>>>>>>>>..........<<<<<<.<<<<<<<<<<<<...>>>>>>
>>>>>>..<<..))>>....>>>>>>.>>>.<<........<<<....>>
>......>>..>>>>>><<<<<...<<<<<....<<<<<<...<<<<<<<
<<......<<........>>..........<<<<<<<.....<<<<<<<.
>>>>>>>..<<.<<...<.<<<<<<<....<<<<<<<<<....>>>.<<<
<......>>>>...>>>>>>.....<<<<<<<<<<<.............>
>>>>>>..<<.<<<......>>>....>>....>>>>.....>>>.>>>.
..>.>.>>>>....>>>>>>>...>>.>>>>>>>.......<<<<<....
..<<<..<<..<<<<....>>>>..>>....>>>......>>>>>.....
.......<....<<<<<<<........>>>>>>>....>.....>>>>>>
....<<<<<<...........>>>>>>..........>>>>>..>>>.>>
....<.<<<.<..<<<<<<<..<<<<<.<<<<<<....<.......<<<<
<<<<<<<.....<<<<<......>>>>>....>>>>>>>>>>>.....>.
..>>>>>>>>>>>..>>>>>>>...>.>>>..>.....<<<<<<<<<...
.>>>>>>>>>.........................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ywx Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): T21 T22 N24 G27 I28 R29 N32 K33 R36 R38 K51 R56 R77 H80 L81 R85 R87 K89 A91 P92 K94 K95 R96 T97 P99
• Binding residue (residue number reindexed from 1): T20 T21 N23 G26 I27 R28 N31 K32 R35 R37 K50 R55 R76 H79 L80 R84 R86 K88 A90 P91 K93 K94 R95 T96 P98

Gene Ontology

Cellular Component

• GO:0005739 mitochondrion
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ywx, PDBe:6ywx, PDBj:6ywx
• PDBsum: 6ywx
• PubMed: 33056988
• UniProt: Q1K5R0|RT27_NEUCR Small ribosomal subunit protein mS33 (Gene Name=rsm27)