Structure of PDB 1vvj Chain YT Binding Site BS01

Receptor Information
>1vvj Chain YT (length=137) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAAKEEAQK
Ligand information
>1vvj Chain XA (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguacuccguggucagcggcggacgggu
gaguaacgcgugggugaccuacccggaagagggggacaacccggggaaac
ucgggcuaaucccccauguggacccgccccuugggguguguccaaagggc
uuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggggua
auggcccaccaaggcgacgacggguagccggucugagaggauggccggcc
acaggggcacugagacacgggccccacuccuacgggaggcagcaguuagg
aaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaa
gaagcccuucgggguguaaacuccugaacccgggacgaaacccccgacga
ggggacugacgguaccgggguaauagcgccggccaacuccgugccagcag
ccgcgguaauacggagggcgcgagcguuacccggauucacugggcguaaa
gggcguguaggcggccuggggcgucccaugugaaagaccacggcucaacc
gugggggagcgugggauacgcucaggcuagacggugggagaggguggugg
aauucccggaguagcggugaaaugcgcagauaccgggaggaacgccgaug
gcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgugg
ggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgc
gcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgcc
gccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggc
ccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaacc
uuaccaggccuugacaugcuagggaacccgggugaaagccuggggugccc
cgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgugc
cgugagguguuggguuaagucccgcaacgagcgcaacccccgccguuagu
ugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcggga
ggaaggaggggacgacgucuggucagcauggcccuuacggccugggcgac
acacgugcuacaaugcccacuacaaagcgaugccacccggcaacggggag
cuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgacc
ccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaa
uacguucccgggccuuguacacaccgcccgucacgccaugggagcgggcu
cuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcccg
ugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcugg
a
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<....>>>>>>>>>.>>>>>......<<
.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......
>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<<<<
...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<...
....>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.
>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>..
......<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<...
...<<<<<..>>>>>.....>>>>....<<<<<........<<<<.....
>>>>..........>>>>>......<<<<<(((...<<<<<.....<<.)
))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((...
..<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>
>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<..
..<<<<<<<.<..<<<......>>>.....>.>>>>>>>...........
<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<
...<<...<<<<.........>>>>...>>>>>>>>..........<<<<
<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.
>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<
......>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<
<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<.
..<...<<<.....>>>.>....>>>>>>>.....<<<<<....>>>>>.
.......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>
.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>
>....>>>.....>>>>>>>......<....<<<<<<<........>>>>
>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<
<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>
>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>..
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1vvj Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Resolution3.44 Å
Binding residue
(original residue number in PDB)		R41 D107 R108 R118 K119 D122 R125
Binding residue
(residue number reindexed from 1)		R41 D107 R108 R118 K119 D122 R125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1vvj, PDBe:1vvj, PDBj:1vvj
PDBsum1vvj
PubMed25128388
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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