Structure of PDB 6hcf Chain Y1 Binding Site BS01

Receptor Information

>6hcf Chain Y1 (length=141) Species: 9986 (Oryctolagus cuniculus)

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

Ligand information

>6hcf Chain A1 (length=1732)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggucaggcggcuuuggugac
ucuagauaaccucgggccgaucgcacgcccggcggcgacgacccauucga
acgucugcccuaucaacuuucgaugguagucgccgugccuaccaugguga
ccacgggugacggggaaucaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacuccc
gacccggggagguagugacgaaaaauaacaauacaggacucuuucgaggc
ccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauugg
agggcaagucuggugccagcagccgcgguaauuccagcuccaauagcgua
uauuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcggc
cguccccugccucucggcgccccggggcccgaagcguuuacuuugaaaaa
auuagaguguucaaagcaggccgccuggauaccgcagcuaggaauaaugg
aauaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauu
aagagggacggccgggggcauucguauugcgccgcuagaggugaaauucu
uggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuu
cauuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucg
uaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauuccc
augacccgccgggcagcuuccgggaaaccaaagucuuuggguuccggggg
gaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccac
caggaguggagccugcggcuuaauuugacucaacacgggaaaccucaccc
ggcccggacacggacaggauugacagauugauagcucuuucucgauuccg
ugggugguggugcauggccguucuuaguugguggagcgauuugucugguu
aauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccc
ggucggcguaacuucuuagagggacaaguggcguucagccacccgagauu
gagcaauaacaggucugugaugcccuuagauguccggggcugcacgcgcg
cuacacugacuggcucagcgugugccuacccuacgccggcaggcgcgggu
aacccguugaaccccauucgugauggggaucggggauugcaauuauuccc
caugaacgaggaauucccaguaagugcgggucauaagcuugcguugauua
agucccugcccuuuguacacaccgcccgucgcuacuaccgauuggauggu
uuagugaggcccucggaucggccccgccggggugcccuggcggagcgcug
agaagacggucgaacuugacuaucuagaggaaguaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucauua

...<<<<<.{.((((>>>>><<<.<<<<<<.....<<..<......<<<.
<<<...<....<<....<<..........>>...>>.>.......<<...
.....<<<.<....<<....<<<<..........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>><<..<<<<<......((((.((.<<..<...>.>>....<.....
.>..>>>>>......>>...<<<<..<<<.>>>.>>>>..>.>>>...>>
..>.>>>.<<<....<<<....<<<<<<<.........>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>...<<....>>.....>>>>>>.........<<<....<<<
.....>>>..>>>..>...>>.......<<<<<<<<<.<<......>>..
>>>>>>.>>>......<<..<...........>..>>.........<<<<
<((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>
>.>>>.........<..[[.....<.<<...<<<.<<....<<<.<<<..
>>>.>>>...........<.<<<.>>>>.........<<<<<<.<.....
..<<...<.......>.<<<<.>>>>...>>......>.>>>..>>>...
.......<<.<<<<<<<......)).))))..>>>>>>>.>>......>>
....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>.
.....>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>>
>...>>>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>.
..>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<......
..>>>>>>>>>.>..>>>...<<..]]>>...>>.....>>>...>.<<<
......<<<......>>>....>>>..)))).}<<<<<.<<<<<<<...<
..<<<<<..<<<.<<<<<<......<<........>>..........<<<
<<......<<<<<........<<.<<<........>>>.>>......>>>
>>...<<.<<<..<<.<<<<<.....<<<.<<<<......>>...<<<..
....>>>...>>.>>>....<<<...<...<<<<..<<<<<<<<.<<<..
>>>..>>>>>>>>..>>>>..>.....<<<<<.....>>>>>........
>>>.....>>.>>>.....>>>>>>>.......>>>>>...>>.>>>>.>
>>.....<<.<<<................<<<.<<<<....>>>>.>>>.
.............>>>.>>............<<<<<..........>>>>
>...........>>>>>.....<<<<<<<<.......>>>>>>>>.....
.>....>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<
<.<<<..<<<<.<<...<<<<<.<<<<<<<<<..>>>>>>>>>...>>>>
>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>........
..<<<<<<<<....>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6hcf ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): G2 K3 R5 R8 T9 R11 K12 R17 R18 Q20 H23 K25 K28 L36 S45 K48 N63 S64 K76 P86 D88 G104 F105 G106 R107 K108 D114 K124 S129 K138
• Binding residue (residue number reindexed from 1): G1 K2 R4 R7 T8 R10 K11 R16 R17 Q19 H22 K24 K27 L35 S44 K47 N62 S63 K75 P85 D87 G103 F104 G105 R106 K107 D113 K123 S128 K137

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 16 00:24:10 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '6hcf', asym_id = 'Y1', bs = 'BS01', title = 'ZNF598 Is a Quality Control Sensor of Collided Ribosomes.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='6hcf', asym_id='Y1', bs='BS01', title='ZNF598 Is a Quality Control Sensor of Collided Ribosomes.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412,0015935', uniprot = '', pdbid = '6hcf', asym_id = 'Y1'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412,0015935', uniprot='', pdbid='6hcf', asym_id='Y1')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>