Structure of PDB 8qu1 Chain Y Binding Site BS01

Receptor Information
>8qu1 Chain Y (length=176) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLEEFFDDPKNWGQEKVKSGAAWTCQQLRNKSNEDLHKLWYVLLKERNML
LTLEQEAKRQRLPMPSPERLDKVVDSMDALDKVVQEREDALRLLQTGQER
ARPGAWRRDIFGRIIWHKFKQWVIPWHLNKRYNRKRFFALPYVDHFLRLE
REKRARIKARKENLERKKAKILLKKF
Ligand information
>8qu1 Chain A (length=938) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccaauaaaguauagg
cgauagaaauugggcgcaauagauauaguaccgcaagggaaagaugaaaa
auaccaagcauaauauagcaaggacuaaccccuauaccuucugaugaauu
aacuagaaauaacuuugcaaggagagccaaagcuaagacccccgaaacca
gacgaagccuggugauagcugguuguccaagauagacaacuuuaaauuug
cccacagaaccaaauccccuuguaaauuuaacuguuaguccaaagaggaa
cagcucuuuggacacuaggaaaaaaccuuguagagagaguaaaaaauuua
acacccauaguaggccuaaaagcagccaccaauuaagaaagcguucaagc
ucaacacucccaaacauauaacugaacuccucacacccaauuggaccaau
cuaucacccuauagaagaacuaauguuaguauaaguaacaugaaaacauu
cuccuccgcauaagccugcgucagaucacugacaauuaacagcccaauau
cuacaaucaaccaacaagucauuauuacccucacugucaacccaaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaaacaucaccucuagcau
caccaguauuagaggccagcugucucuuacuuuuaaccagugaaauugac
cugcccgugaggcgggcauaacacagcaagacgagacccuauggagcuuu
aauuuauuaaugcaaacaccugcauuaaaaauacaugcuaagacuucacc
agucaaagcgaacaguuacccuaggguaucuacuuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucuaaaugau
aucaucucaacuuaauacccacacccaagaacaggguu
<<<.......<<<<................................<<..
...>>.......>>.>>.............<<....>>............
......>>>...........<<<.......>>>...<.<....>.>.<<<
<<<.........<<<.<<..<<....>>...>>.>>>...<<.<..<<<<
<.<...>.>>>>...>..>.>>..<<<<<<....<.><<<.<<<<<<<<<
<.....<<......>>.....>>>>>>>>>>..>>>.<<<<<<<<<<...
...>>>>>>>>>>...<<<......>>>....<<<.<<<...<.......
.......<....<<<.........>>>....>.......<<<......>>
>.....................>...>>>>>>........>>>>>>...<
<<<<......>>>>>.........>>>>>><......<<..<<<....>>
><<<<..<<<<........<<<<<....>>>>>......<<<...<<<<.
......................>>>>.......>>>.....<<..>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<<<<<<....
.........>>>>>>........>>.>>>>>>>>>>>>.>>.....>...
..<<<<<.....>>>>>.......<<..<<<.....<<<<<.<<<<<<..
..<<..<<<<<<<<......>>>>>>>.>>>.....<<<..<<<<.....
>>>>..>>>....>>>>..>>>>>>>..>>>.>>..<<<.<<<.......
..........>>>.>>><<<<<...<<<....>>>.>>>>>.<<<.<...
.........>.>>>........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qu1 GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		Q117 K120 R121 R123 R162 R164 W178 K180 K182 I186 K192 R193 R196 K197 R198 R213 R216 R222 N225 L226 K229 K230
Binding residue
(residue number reindexed from 1)		Q55 K58 R59 R61 R100 R102 W116 K118 K120 I124 K130 R131 R134 K135 R136 R151 R154 R160 N163 L164 K167 K168
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qu1, PDBe:8qu1, PDBj:8qu1
PDBsum8qu1
PubMed38969660
UniProtQ9HD33|RM47_HUMAN Large ribosomal subunit protein uL29m (Gene Name=MRPL47)

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