Structure of PDB 8qbn Chain Y Binding Site BS01

Receptor Information
>8qbn Chain Y (length=119) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNL
QYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVIL
ERALVRESEGFEEHVPSDN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8qbn Chain Y Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qbn Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C17 C73 C76
Binding residue
(residue number reindexed from 1)		C16 C72 C75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008283 cell population proliferation
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0000922 spindle pole
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005856 cytoskeleton
GO:0030496 midbody
GO:0097431 mitotic spindle pole
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qbn, PDBe:8qbn, PDBj:8qbn
PDBsum8qbn
PubMed38759627
UniProtP62699|YPEL5_HUMAN Protein yippee-like 5 (Gene Name=YPEL5)

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