Structure of PDB 8pr4 Chain Y Binding Site BS01

Receptor Information
>8pr4 Chain Y (length=375) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYC
PSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTS
RDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLA
RRKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICA
SQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEV
RIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVS
VPPTELVLAGEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFK
LKHDFKNLGAEVSWLTQHVELSLGP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8pr4 Chain Y Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pr4 Molecular mechanism of dynein-dynactin complex assembly by LIS1
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C30 C284
Binding residue
(residue number reindexed from 1)		C29 C218
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005856 cytoskeleton
GO:0005869 dynactin complex
GO:0005938 cell cortex
GO:0030017 sarcomere

View graph for
Cellular Component
External links
PDB RCSB:8pr4, PDBe:8pr4, PDBj:8pr4
PDBsum8pr4
PubMed38547289
UniProtA0A4X1TB62|DCTN4_PIG Dynactin subunit 4 (Gene Name=DCTN4)

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