Structure of PDB 8p2h Chain Y Binding Site BS01
Receptor Information
>8p2h Chain Y (length=94) Species:
93061
(Staphylococcus aureus subsp. aureus NCTC 8325) [
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SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVI
REVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINM
Ligand information
>8p2h Chain B (length=113) [
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cuggugacuauagcaaggaggucacaccuguucccaugccgaacacagaa
guuaagcuccuuagcgucgaugguagucgaacuuacguuccgcuagagua
gaacguugccagg
<<<<<<<<....<<<<<<<<.....<<<<<...............>>>..
>>....>>>>>>.>>.<<......<<<.<<<<....>>>>.>>>......
>>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8p2h
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric hybrid state
Resolution
2.49 Å
Binding residue
(original residue number in PDB)
T14 R15 S16 L18 K19 R22 V30 Y32 N38 S40 Q78 H88
Binding residue
(residue number reindexed from 1)
T12 R13 S14 L16 K17 R20 V28 Y30 N36 S38 Q76 H86
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:8p2h
,
PDBe:8p2h
,
PDBj:8p2h
PDBsum
8p2h
PubMed
38902339
UniProt
Q2G0S0
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