Structure of PDB 8i0u Chain Y Binding Site BS01

Receptor Information
>8i0u Chain Y (length=320) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFI
IQTGDPTGTGRGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNG
SDQHGSQFLITTGENLDYLDGVHTVFGEVTEGMDIIKKINETFVDKDFVP
YQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEIDDF
KGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPV
TTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFK
MDNVLIDDRRIHVDFSQSVA
Ligand information
>8i0u Chain G (length=79) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cggccuccgaacgguaagagccuagcauguagaacugguuaccuaugaug
ucauacuuauccugucccuuuuuuuucca
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Receptor-Ligand Complex Structure
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PDB8i0u Molecular basis for the activation of human spliceosome
Resolution3.3 Å
Binding residue
(original residue number in PDB)		C245 K246 H312
Binding residue
(residue number reindexed from 1)		C245 K246 H312
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:8i0u, PDBe:8i0u, PDBj:8i0u
PDBsum8i0u
PubMed39068178
UniProtQ8WUA2|PPIL4_HUMAN Peptidyl-prolyl cis-trans isomerase-like 4 (Gene Name=PPIL4)

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