Structure of PDB 8etj Chain Y Binding Site BS01

Receptor Information
>8etj Chain Y (length=125) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFSRDVTSSRRKQRKAHFGAPSSVRRVLMSAPLSKELREQYKIRSLPVR
RDDQITVIRGSNKGREGKITSVYRKKFLLLIERVTREKANGASAPVGIDA
SKVVITKLHLDKDRKDLIVRKGGKV
Ligand information
>8etj Chain 1 (length=1817) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaaugggugguaaauuucauc
uaaagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucga
aagaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcug
aaagggaagcauuggaaaucaggucagcaucaguuuucgggggcggaaaa
agaauaagggaagguggcuuuccgggaguguuuauagcccuuguuguaau
acguccacuggggacugaggacugcggcuucgugccaaggaugcugacau
aaugguuuucaauggcccgucuacacggaccaaggagucuagcaucuaug
cgaguguuugggugaugaaaacccauccgcgaaaugaaagugaaugcagg
ugggaacgcccuuguggcgugcaccaucgaccgacccggaaguauggaag
gguuugaguaagagcauagcuguugggacccgaaagauggugaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaaacucagauc
aguuuuaugaguauguaaaaugagaguuucuagugggccauuuuugguaa
gcagaacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaa
uguacgcucaucagaagaaaagguguuaguucaucuagacagcaggacgg
uggccauggaagucggaauccgcuaaggaguguguaacaacucaccugcc
gaaugaacuagcccugaaaauggauggcgcuuaagcguacuacccauacc
ucaccgucuggguugaagcucagacgaguaggcaggcguggagguuugug
acgaagccuugggcgugagccugggucgaacagccucuagugcagaucuu
gguggaaguagcauucaaaugagaacuuugaagacugaaguggggaaagg
uuccaugugaacagcaguuggacauggguuccaaggugaacagccucuag
uugauagaacaauguagauaagggaagucggcaaaaugccacugucccua
ucuacuaucuagcgaaaccacagccuggggaacgggccaggcaaaaucag
cggggcuuguggcagucaagcggcgacauugcuuuccuaucauaccgaag
cagaauucgguaagcguuggacccacuaauagggacuacugaugaagugu
cgucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauc
auugguauuugcggcugccugacaaggcaaugccgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gauuuuuugguccgcaugauuuauauguauaaaaauagagguaggcuacu
cuccuguaucguagaagaugggcgaugguugaugaaacggaaguguuuua
uugacuuguccaugaaauuccaaucuugugcggaaucgaauccauugcau
acgacuuuaauguggaacgggguauuguaagcagcugcugagauuaagcc
uuuguucccaagauuug
.........................<<<<<........>>>>>.......
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<..
......<<.<<<<<<<.......>>>>>>>.>>........>....<<<<
<.<<<<<..<<<<<...<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>...>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<<......>>>>>
>..>>>..................................<<....>>..
.............<<<<....>>>>.........................
.........<<<<<<<<<<<<.<<<<<<<.<<<<<<<<<<<<<<<.....
...<<<<<<<......<.<<<<..>>>>..>......>>>>>>>......
.>>>>>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>..
..>>>>>>>>>>>>..<<<<....>>>><<<<<<....<<<<<<.<<<<<
<..<<<..<<<<<.......>>>>>..>>>...<<....>>.......<<
<<<..<<<<<.....>>>>>...>>>>>.<<<<<<<<....<<>>....>
>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<..>>>>>>.
.....>.>>..<<<<<<.......<<....>>...<<<<<<<<<<...<<
<.<<<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<.<<....
.>>.>>.>>>>....<<<......>>>...<<<<<<<...<<<(((....
.<<<<<<.....<<......<<<.<<<<<<<<<<.......<<<<<.<<.
...<<.........>>....>>.........<<......>>...>>>>>.
..>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>...>>>
>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<<<<.<<.
.....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>
>>><<.....<<.<<<<<<.......>>>>>><<<<<....<<<......
..<<<<<....<<.....>>..>>>>>..>>>.<<<<.....>>>>.>>>
>>..<<<<.....<<<<<<<.<<.........<.........>..>>.>>
>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<
..<.......<<<<<<...<<.>>...>>>>>><<<<<..<.<<<<<<<.
.....>>>>>>>...>.<<<..>>>.....>>>>>.>.>>>>>.....<<
<<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<.
..<<<<....<<<<<<<<<<....>>>>>..>>>>>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>>>.....<.<<<..<.<..........<<.......<<<<..<..>..>
>>>....>>........<<<<<....<<<<<<<<<<<<......>>>>>>
>>>>>>..>>>>>.............>.>..>>>.>.<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<..>>>...>>>....>>
>>.>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8etj Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		M1 K2 F3 R5 V7 T8 S9 R11 K13 Q14 R15 H18 V28 L29 S31 P33 K36 R45 S46 I58 R59 G60 S61 R86 K88 N90 S101 K102 R120
Binding residue
(residue number reindexed from 1)		M1 K2 F3 R5 V7 T8 S9 R11 K13 Q14 R15 H18 V28 L29 S31 P33 K36 R45 S46 I58 R59 G60 S61 R86 K88 N90 S101 K102 R120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8etj, PDBe:8etj, PDBj:8etj
PDBsum8etj
PubMed36423630
UniProtP78946|RL26_SCHPO Large ribosomal subunit protein uL24 (Gene Name=rpl26)

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