Structure of PDB 8c8h Chain Y Binding Site BS01

Receptor Information
>8c8h Chain Y (length=539) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLL
LFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWMNTILRYA
PEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLI
KEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLR
PGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFA
KKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFNDFK
NSLRDREFSKSALDTFKKGELLKGDASAADISLFTELKEKSVKFIDVCLG
ILASHGKCLVFEPFQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEF
NQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGR
AIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQSKSKEFVQ
LFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDL
Ligand information
>8c8h Chain U (length=63) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaugguguaaugguuagcacucuggacuuugaauccagcgauccgaguu
caaaucucggugg
<<<..<<<<........>>>>.<<<<<.......>>>>>....<<<<<..
.....>>>>>>>>
Receptor-Ligand Complex Structure
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PDB8c8h Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Resolution3.84 Å
Binding residue
(original residue number in PDB)		R120 F124 K153 K157 I158 R159 R162 S163 N166 K170 K175 H208
Binding residue
(residue number reindexed from 1)		R118 F122 K151 K155 I156 R157 R160 S161 N164 K168 K173 H206
Enzymatic activity
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c8h, PDBe:8c8h, PDBj:8c8h
PDBsum8c8h
PubMed
UniProtP05807|NTP1_VACCW Nucleoside triphosphatase I (Gene Name=OPG123)

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