Structure of PDB 8c3a Chain Y Binding Site BS01

Receptor Information
>8c3a Chain Y (length=129) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLTVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVIQPRFNVKINDIERWTDNLLPARQFGY
VILTTSAGIMDHEEARRKHVSGKILGFVY
Ligand information
>8c3a Chain B (length=1761) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccgcguacuggacccagccgagccuuuccuucuggguagccauuu
auggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuaugguu
cuauuuuguugguuucuaggaccaucguaaugauuaauagggacggucgg
ggguaucaguauucaguugucagaggugaaauucuuggauuuacugaaga
cuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaagaacg
aaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccauaa
acuaugccgacuagggaucgguuguuguucuuuuauugacgcaaucggca
ccuuacgagaaaucaaagucuuuggguucuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcuuaauuugacucaacacggggaaacucaccagguccagacacaaua
aggauugacagauugagagcucuuucuugauuuugugggugguggugcau
ggccguucuuaguugguggagugauuugucugcuuaauugcgauaacgaa
cgagaccuuaaccuacuaaauagugcugcuagcauuugcugguauaguca
cuucuuagagggacuaucgauuucaagucgauggaaguuugaggcaauaa
caggucugugaugcccuuagacguucugggccgcacgcgcgcuacacuga
cggagccagcgaguauaagccuuggccgagaggucugggaaaucuuguga
aacuccgucgugcuggggauagagcauuguaauuguugcucuucaacgag
gaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccugcc
cuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagugaggc
cuccggauugguuuaggaaauucuggaaccgagaagcuggucaaacuugg
ucauuuagaggaaguaaaagucguaacaagguuuccguaggugaaccugc
ggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<...............<<.....<..<
<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......((((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
....................>>>>>>>>>>.....<<<<<..........
........>>>>>....<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<<<<<<
<<......))))))...>>>>>>>>>>>.....>>....<<<<<<.<<..
.<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..
>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>.
...<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.....
.....<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>>>..
>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<....>
>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<
<<<<......<<........>>..........<<<<<......<<<<<..
......<<.<<<........>>>.>>......>>>>>...<<.<<<..<<
.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>>.>>
>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>
>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.....>
>.>>>.....>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<
<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.....
..>>>>>>>......<....<<<<<<..........>>>>>>....>...
..>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>
>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<
<..<...<<<<<<.............>>>>>>...>..>>>>..>>>.>>
>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>
>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c3a New crystal system to promote screening for new eukaryotic inhibitors
Resolution3.0 Å
Binding residue
(original residue number in PDB)		T2 R3 T4 V6 A8 N12 N16 R28 S30 S31 K32 H56 R57 S58 K71 V74 I75 Q76 R78 N80 K82 R88 W89 T105 T106 S107 R118 K119 H120 S122 K124 Y130
Binding residue
(residue number reindexed from 1)		T1 R2 T3 V5 A7 N11 N15 R27 S29 S30 K31 H55 R56 S57 K70 V73 I74 Q75 R77 N79 K81 R87 W88 T104 T105 S106 R117 K118 H119 S121 K123 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum8c3a
PubMed
UniProtA0A8H6F0N4

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