Structure of PDB 7y38 Chain Y Binding Site BS01

Receptor Information
>7y38 Chain Y (length=466) Species: 371094 (Chikungunya virus strain S27-African prototype) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIIETPRGAIKVTAQPTDHVVGEYLVLSPQTVLRSQKLSLIHALAEQVKT
CTHSGRAGRYAVEAYDGRVLVPSGYAISPEDFQSLSESATMVYNEREFVN
RKLHHIAMHGPALNTDEESYELVRAERTEHEYVYDVDQRRCCKKEEAAGL
VLVGDLTNPPYHEFAYEGLKIRPACPYKIAVIGVFGVPGSGKSAIIKNLV
TRQDLVTSGKKENCQEITTDVMRQRGLEISARTVDSLLLNGCNRPVDVLY
VDEAFACHSGTLLALIALVRPRQKVVLCGDPKQCGFFNMMQMKVNYNHNI
CTQVYHKSISRRCTLPVTAIVSSLHYEGKMRTTNEYNKPIVVDTTGSTKP
DPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTRKGVYAVRQKVNEN
PLYASTSEHVNVLLTRTEGKLVWKTLSGDPWIKTLQNPPKGNFKATIKEW
EVEHASIMAGICSHQM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y38 Molecular architecture of the Chikungunya virus replication complex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y161 F164 K210 K211 D235
Binding residue
(residue number reindexed from 1)		Y161 F164 K210 K211 D235
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7y38, PDBe:7y38, PDBj:7y38
PDBsum7y38
PubMed36449616
UniProtQ8JUX6|POLN_CHIKS Polyprotein P1234

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