Structure of PDB 7ohu Chain Y Binding Site BS01

Receptor Information
>7ohu Chain Y (length=125) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIR
RDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHP
SKLVITKLHLDKDRKALIQRKGGKL
Ligand information
>7ohu Chain 1 (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuauaucaauaagc
ggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcgg
caaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuu
ggagagggcacuuuggggccguuccuugucuauguuccuuggaacaggac
gucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaa
gugccuucgaagagucgaguuguuugggaaugcagcucuaaguggguggu
uccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagu
gauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaa
uuguugaaagggaagggcauuugaucagacaugguguuuuguggggaauc
ucgcauuucacugggccagcaucaguuuugguggcaggauaaauccauag
gaauguagcuugccucgguaaguauuauagccugugggaauacugccagc
ugggacugaggacugcgacguaagucaaggaugcuggcauaaugguuaua
ugccgccgucuugaaacacggaccaagggucuaacgucuaugcgaguguu
uggguguaaaacccauacgcguaaugaaagugaacguagguuggggccuc
gcaagaggugcacaaucgaccgauccugaggauggauuugaguaagagca
uagcuguugggacccgaaagauggugaaaccaucuaguacugguuccugc
cgaaguuucccucaggauagcagaagcucguaucaguuuuauuaaaauga
agagcuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaug
aaccgaacguagaguuaaggugccggaauacacgcucaucagaccaaaag
guguuaguucaucuagacagccggacgguggccauggaagucggaauccg
cuaaggaguguguaacaacucaccggccgaaugaacuagcccugaauggc
gcucaagcguguuaccuauacucuaccgucaggguugauaugaugcccug
acgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucg
ggucgaacggccucuagugagaucuuggugguaguagcagcgaaaccaca
gccaagggacgggcuuggcagaaucagcgggggcuuguggcagucaagcg
gcgacauugcucauaccgaagcagaauucgguaagcgucuacugaugaug
uuaccgcaauaguaauugaacuuaguacgagaggaacaguucauucggau
aauugguuuuugcggcugucugaucaggcagccgcgaagcuaccauccgc
uggauuauggcugaacgccucuaagucagauccaugcuagaacgcgguga
uuucuuugcuccacacaauauagauggauacgaauaaggcguccuugugg
cgucgcugaaccauagcaggcuagcaacggugcacuuggcggaaaggccu
ugggugcuugcuggcgaauugcaaugucauuuugcguggggauaaaucau
uuguauacgacuuagauguacaacgggguauuguaagcaguagaguagcc
ugguuacgaucugcugagauuaaccuuuguugucugauuugu
..........................<<<<<<...............>>>
>>.>.........<<....>>..<<<<<......<<.....>>.....>>
>>>..<<<..<........<<.<<<<<<...>>>>>>.>>........>.
...<<<<<<<<<<..<<<<<<<<<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>>..>>>>>>>......>>
>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<.
.>>>>>>..>>>..................................<<..
..>>...............<<<<....>>>>...................
...............<<<<<.<<<<<.<....<<<<...<<<........
..>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<.....<<<<<<<<
<......<<<<<......>>>>>.......>>>>>>>.>.>.>>>>>.>>
>>>>>>>>........<<<....>>>.....>>>>>>>....>>>>>>.>
>>>>.<<<<........>>>><<<<<<...<<<<<<.<<<<<<..<<<..
.<<<<.....>>>>...>>>..................<<<<<..<<<<<
....>>>>>...>>>>>.<<<<<<<<.......>>>.>>>.>>....>>>
>>>.>>>>>>..<<.<...<<<<<<...>>>>>>.....>.>>..<<<<<
<....<.<<......>>.><<<<<<<<<....<<<.<<<<...>>>>>>>
..>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<....
..>>>...<<<<<<<..<<<<(((.....<<<<<<......<......<<
<.<<<<<<<<<<.......<<<<<.<<....<<.........>>....>>
.........<<......>>...>>>>>...>>>>>>>>>>>>>....)))
.>....>>>>>>.>>>>..>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>..>....>>>>>><<.....<<.>>....>>...
.<<<<<.......>>>>>....<<<<<..<.........<<<<....<<.
>>....>>>>...<<<<<<<......>>>>>>>......>.>>>>>...<
<<<<<<<..<<<<.<.<<<<<<...............>>>>>>.><<<<<
...<<......<<<<<<<<........>>>>>>>>.....>>..>>>>>.
<<<<...<<<<<...........>>>>>..>>>>.>>>>....>>>>>>>
>.......<<<<<<.<<<.<<....<<..........<<<<<<.....>>
>>>>......>>.......<<<<<<...<<<<<.<..<<<......>>>.
.>.>>>>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<
.............>.....<<<<<<<<<.<<<....<<<<....<<.<<.
..>>.>>...>>>>...>>>...>>>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
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PDB7ohu Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
A2 K3 Q4 S5 L6 S9 S10 R12 R16 Y19 V29 L30 P34 R40 K46 R60 S62 K89 V90 N91 H100 S102 K103 K122
Binding residue
(residue number reindexed from 1)
A1 K2 Q3 S4 L5 S8 S9 R11 R15 Y18 V28 L29 P33 R39 K45 R59 S61 K88 V89 N90 H99 S101 K102 K121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0032991 protein-containing complex
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohu, PDBe:7ohu, PDBj:7ohu
PDBsum7ohu
PubMed34813592
UniProtP05743|RL26A_YEAST Large ribosomal subunit protein uL24A (Gene Name=RPL26A)

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