Structure of PDB 7ohs Chain Y Binding Site BS01

Receptor Information
>7ohs Chain Y (length=125) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIR
RDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHP
SKLVITKLHLDKDRKALIQRKGGKL
Ligand information
>7ohs Chain 1 (length=1697) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaau
aagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaa
gcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguugua
auuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaac
aggacgucauagagggugagaaucccguguggcgaggagugcgguucuuu
guaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugg
gugguuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaagu
acagugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacg
ugaaauuguugaaagggaagggcauuugaucagacaugguguuuugugcc
cucugcuccuuguggguaggggaaucucgcauuucacugggccagcauca
guuuugguggcaggauaaauccauaggaauguagcuugccucgguaagua
uuauagccugugggaauacugccagcugggacugaggacugcgacguaag
ucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggac
caaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgu
aaugaacgagguuggggccucgcaagaggugcacaaucgaccgauccuga
ggauggauuugguaagagcauagcuguugggacccgaaagauggugaaaa
ccaucuaguagcugguuccugccgaaguuucccucaggauagcagaagcu
cguaucaguuuuaugaguaagaaugaagagcuuuuagugggccauuuuug
guaagcagaacuggcgaugcgggaugaaccgaacguagaguuaaggugcc
ggaauacacgcucaucagaacaaaagguguuaguucaucuagacagccgg
acgguggccauggaagucggaauccgcuaaggaguguguaacaacucacc
ggccgaaugaacuagcccugaggauggcgcucaagcguguuaccuauacu
cuaccgucaggguugauaugaugcccugacgaguaggcaggcguggaggu
cagugacgaagccuagaccguaaggucgggucgaacggccucuagugcag
aucuuggugguaguagcagcgaaaccacagccaagggaacgggcuuggca
gaaucagcggggcagucaagcggcgacauugcuaucauaccgaagcagaa
uucgguaagcgucuacugaugaauguuaccgcaauaguaauugaacuuag
uacgagaggaacaguucauucggauaauugguuuuugcggcugucugauc
aggcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucua
agucagaauccaugcuagaacgcggugaugcuccacacagauggauacga
auaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggugc
acuuggcggaaaggccuugggugcuugcuggcgaauugcaaugcgugggg
auaaaucauuuguauacgacuuagauguacaacgggguauuguaagcagu
agaguagcguuacgcugcugagauuaagccuuuguugucugauuugu
..........................<<<<<<..................
.>>>>>.>.........<<....>>..<<<<<......<<.....>>...
..>>>>>..<<<..<........<<.<<<<<<...>>>>>>.>>......
..>....<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......
>>>>.((......<<<.....))>>>....>>>>>>>>..>>>>>>>>..
..>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<
<<<....>>>>>..>>>.................................
.<<....>>...............<<<......>>>..............
....................<<<<<.<<<<<<.....<<<<...<<<<.<
<<<<<<<<.....>>>>>>>>>.....>>>>...>>>>..<<<<<<<.<<
<<<<<<<<<<<<<......<<<<<<<<......<<<<<......>>>>>.
......>>>>>>>>....>>>>>.>>>>>>>>>>........<<<....>
>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<
<<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>..
.........<<<<<..<<<<<....>>>>>...>>>>>...<<..<<...
....>>...>>......>>>>>>.>>>>>>..<<.<...<<<<<<....>
>>>>>......>.>>..<<<<<<......<<......>>..<<<<<<<<<
.....<<.<<<<<<..>>>>.>>>>...>>>>>>>.>>..<<<<.<.<..
.......>.>.>>>>....<<<......>>>...<<<<<<<..<<<<(((
.....<<<<<<......<......<<<.<<<<<<<<<<.......<<<<<
.<<<...<<.........>>...>>>.........<<......>>...>>
>>>...>>>>>>>>>>>>>......))).>....>>>>>>.>>>>..>>>
>>>><<<<<<<<<.........>>>>>>>>>....>>>>>><..<<<<<<
<.<<......<<<<.<<<<....>>>>>>>>...>>>>>>>>>...>...
..>>>>>><<.....<<.>>....>>....<<<<<........>>>>>..
...<<<......<<<....<<.>>....>>>....<...<<<<<......
>>>>>.....>.....>>>.....<<<<<<<<..<<<<.<.<<<<<<...
..<....>....>>>>>>.><<<<<...<.......<<<<<.........
.......>>>>>......>..>>>>>.<<<<...<<<<<...........
>>>>>...>>>>.>>>>....>>>>>>>>.<<<<<<......<<......
....<<<<<.<....>>>>>>......>>.......<<<<<<...<<<<<
....<<<......>>>....>>>>>.>>>>>>............>>>>>>
.<<<<<<.<.............>.....<<<<<.<<<.<<<.....<<<.
..............>>>....>>>....>>>..>>>>>..>>>>>>.
Receptor-Ligand Complex Structure
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PDB7ohs Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution4.38 Å
Binding residue
(original residue number in PDB)
A2 K3 L6 V8 S9 S10 R12 V29 L30 S32 P34 R40 K46 R60 G61 K87 K89 V90 N91 H100 S102 K103 R121 K122
Binding residue
(residue number reindexed from 1)
A1 K2 L5 V7 S8 S9 R11 V28 L29 S31 P33 R39 K45 R59 G60 K86 K88 V89 N90 H99 S101 K102 R120 K121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0032991 protein-containing complex
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohs, PDBe:7ohs, PDBj:7ohs
PDBsum7ohs
PubMed34813592
UniProtP05743|RL26A_YEAST Large ribosomal subunit protein uL24A (Gene Name=RPL26A)

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