Structure of PDB 6wqq Chain Y Binding Site BS01

Receptor Information
>6wqq Chain Y (length=136) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESA
RIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPG
RILFEVAGVSEEVAREALRLASHKLPVKTKFVKREE
Ligand information
>6wqq Chain 1 (length=2698) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaa
ggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugau
ccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucg
auaugugaauacauagcauaucagaaggcacacccggagaacugaaacau
cuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggcg
agcgaaacgggaagagcccaaaccaacguugggguuguaggacacucuag
uuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaag
guaauaauccuguagucgaaaauguugucucucuugaguggauccugagu
acgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaa
ggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaag
gugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcu
uacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaau
gaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagcc
guagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccg
aaaccaggugaucuacccuuggucagguugaaguucagguaacacugaau
ggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggua
gcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauag
cuuuagggcuagccucaagugaugauuauuggagguagagcacuguuugg
acgagcgaauucagacaaacuccgaaugccaauuaauuuaacuugggagu
cagaacaugggugauaagguccguguucgaaagggaaacagcccagacca
ccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguugc
cacagagugacacugcgccgaaaauguaccggggcuaaacauauuaccga
agcuguggauuguccuuuggacaaugguaggagagcguucuaagggcguu
gaagcaugaucguaaggacauguggagcgcuuagaagugagaaugccggu
gugaguagcgaaagacgggugagaaucccguccaccgauugacuaagguu
uccagaggaaggcucguccgcucuggguuagucggguccuaagcugaggc
cgacaggcguaggcgauggauaacagguugauauuccuguaccaccuaua
aucguaucgauggggggacgcaguaggauaggcgaagcgugcgauuggau
ugcacgucuaagcaguaaggcuguccgguagcugagcugugauggggaga
agaccuucgagucguugauuucacacugccgagaaaagccucuagauaga
aaauaggugcccguaccgcaaaccgacacagguagucaagaugagaauuc
uaaggugagcgagcgaacucucguuaaggaacucggcaaaaugaccccgu
aacuucgggagaaggggugcucuuuaggguuaacgcccagaagagccgca
gugaauaggcccaagcgacuguuuaucaaaaacacaggucucugcuaaac
cguaaggugauguauaggggcugacgccugcccagugcuggaagguuaag
aggagugguuagcuucugcgaagcuacgaaucgaagccccaguaaacggc
ggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaagu
uccgacccgcacgaaaggcguaacgauuugggcacugucucaacgagaga
cucggugaaaucauaguaccugugaagaugcagguuacccgcgacaggac
ggaaagaccccguggagcuuuacuguagccugauauugaaauucggcuuu
cuaacccgcaccacuuaucguggugggagacagugucaggcgggcaguuu
gacuggggcggucgccuccuaaaagguaacggaggcgcucaaagguuccc
ucagaaugguuggaaaucauucauagaguguaaaggcauaagggagcuug
acugcgagaccuacaagucgagcagggucgaaagacggacuuagugaucc
ggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgg
ggauaacaggcuuaucucccccaagaguucacaucgacggggagguuugg
caccucgaugucggcucaucgcauccuggggcuguagucggucccaaggg
uugggcuguucgcccauuaaagcgguacgcgagcuggguucagaacgucg
ugagacaguucggucccuauccgucgugggcguaggaaauuugagaggag
cuguccuuaguacgagaggaccgggauggacauaccucugguguaccagu
ugucgugccaacggcauagcuggguagcuauguguggacgggauaagugc
ugaaagcaucuaagcaugaagccccccucaagaugagauuucccaacuuc
gguuauaagaucccucaaagaugaugagguuaauagguucgagguggaag
cauggugacauguggagcugacgaauacuaaucgaucgaagacuuaau
<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<......
<<<<<<.((..((.>>>.....<<<<<<<..<<.))..))..>>.....>
>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<
<<<<<...........>>>>>>.>>.>>....<<<<<......<......
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<..>>>>......<<<<<<<.....
........<..<<<<<<.<<<...<<<<<......>>>>>((......<<
<.....))>>>...>>>...>>>>>>...>.......>>>..>>>>....
.<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..
)))......]].>>>>>>>.]]...............<<....>>....]
].........<<<<....>>>>.............}....>>>>>>>>>>
>.......<<<<..<<<<......>>>>..>>>>...<.<........>.
>.<<<<<<....<<<<<<<.<<<<<..<<<...<<.......>>...>>>
...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<
...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>
.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>.
..<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<
<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<
<........>>>>>>>>..>>.>.....>>>>.>>>>>..>>>>>>>.>>
..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<<<.
.......>>>>.>>>>.>>...........))).....>>>>>>.>>>..
.>>>>>>><<<<<<.....>>>>>>....>>>>>>..<<<<<<<.<<...
...<<<<<.<<....>>.>>>>>...>>.>>>>>>>........>>>>>>
<......<<....<<<<<<.......>>>>>><<<<....<<<<<.<<..
.<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<
<....>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<.
......<<...<<<<....<<<<...<<...<......<<..........
.>>...<<...<<<<...<<<.........>>>...>>>>....>>....
.<....>........>....>>...>>>>.........>>>>..>>....
..>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<.......>>
>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<..
...<..>......>>>>><<<<<<<.<<<<....>>>>.>>>>>>>....
........<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<
<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<
<...<<<<<..<<....>>...>>>>>...>>..>>>>>>>>>..>>>>>
<<<<<.........>>>>>........<...........<<<<<......
.>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.
>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(((.
[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<.<..>.>>>
>....<<.<<<<<.......>>>>>>>.....>>>>>>>>>..>>>>>..
<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<
...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>..
.<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<
<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>
>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>
>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>
.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<.
...>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..
<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<
<<<<<......>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<
<...........>>>>>...>>>>.>>>>.......>>>>>>>.<<<...
.>>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<
<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wqq Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		P4 K5 R6 Y9 R11 H13 R14 K22 F29 Q46 S49 R56 K63 W65 F69 H71 K77 R82 M83 G84 A85 G86 K87 R101 H123 K124 P126 K128
Binding residue
(residue number reindexed from 1)		P4 K5 R6 Y9 R11 H13 R14 K22 F29 Q46 S49 R56 K63 W65 F69 H71 K77 R82 M83 G84 A85 G86 K87 R101 H123 K124 P126 K128
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6wqq, PDBe:6wqq, PDBj:6wqq
PDBsum6wqq
PubMed32566908
UniProtQ2FW13|RL16_STAA8 Large ribosomal subunit protein uL16 (Gene Name=rplP)

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