Structure of PDB 6gc4 Chain Y Binding Site BS01

Receptor Information
>6gc4 Chain Y (length=63) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDV
ARVKTLLNEKAGA
Ligand information
>6gc4 Chain A (length=2586) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaucuagccaugggcag
guugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaa
aaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccggga
gauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucau
cuccggggguagagcacuguuucggcaagggggucaucccgacuuaccaa
cccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacgg
cgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcua
aggucccaaagucaugguuaagugggaaacgaugugggaaggcgucggcc
ugcgcggaagauguaacggggcuaaaccaugcaccgaagcugcggcagcg
acgcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggug
ugcugugaggcaugcuggagguaucagaagugcgaaugcugacauaagua
acgauaaagcgggugaaaagcccgcucgccggaagaccaaggguuccugu
ccaacguuaaucggggcagggugagucgaccccuaaggcgaggccgaaag
gcguagucgaugggaaacagguuaauauuccuguacuugguguuacugcg
aaggggggacggagaaggcuauguuggccgggcgacgguugucccgguuu
aagcguguaggcugguuuuccaggcaaauccggaaaaucaaggcugaggc
gugaugacgaggcacuacggugcugaagcaacaaaugcccugcuuccagg
aaaagccucuaagcaucagguaacaucaaaucguaccccaaaccgacaca
gguggucagguagagaauaccaaggcgcuugagagaacucgggugaagga
acuaggcaaaauggugccguaacuucgggagaaggcacgcugauauguag
gugaggucccucgcggauggagcugaaaucagucgaagauaccagcuggc
ugcaacuguuuauuaaaaacacagcacugugcaaacacgaaaguggacgu
auacggugugacgccugcccgguguaaacggcggccguaacuauaacggu
ccuaagguagcgaauggcguaaugauggccaggcugucuccacccgagac
ucagugaaauugaacucgcugugaagaugcaguguacccgcggcaagacg
gaaagaccccgugaaccuuuacuauagcuugacacugaacauugagccuu
gauguguaggauaggugggaggcuuugaaguguggacgccagucugcaug
gagccgaccuugaaauaccacccuuuaauguuugauguucuaacguugac
ccguaauccggguugcggacagugucugguggguaguuugacuggggcgg
ucuccuccuaaagaguaacggaggagcacgaagguuggcuaauccugguc
ggacaucaggagguuagugcaauggcauaagccagcuugacugcgagcgu
gacggcgcgagcaggugcgaaagcaggucauagugauccggugguucuga
auggaagggccaucgcucaacggauaaaagguacuccggggucccuaucu
gccgugggcgcuggagaacugaggggggcugcuccuaguacgagaggacc
ggaguggacgcaucacugguguucggguugucaugccaauggcacugccc
gguagcuaaaugcggaagagauaagugcugaaagcaucuaagcacgaaac
uugccccgagaugaguucucccugacccuuuaaggguccugaaggaacgu
ugaagacgacgacguugauaggccggguguguaagcgcagcgaugcguug
agcuaaccgguacuaaugaaccgugaggcuuaaccu
<<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]].....
..........<<....>>....]].........<<<<.....>>>>....
.........}....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<
<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<......
..>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>.
.....>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<
<<<<<<......<<...<<<.<<<<......<<.........>>......
.>>>>.>>>..>>.......>>>>>>.>>>...>>>>>>>.>...<<<<<
<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<..
.<<<(((.....<<<<<<...........<<..<<<<<..<<..>>..>>
>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<
..<......>..>>>>>....>>>>>><<<<<<<...<<<......<<<<
<<<<....>>>>>>>>...>>>..>>>>>.>>.....>>>>>><......
<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<
<...<<.....>>.>>>>>>....((<<<.<<<...<<<...<<<....>
>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<<<<.
..<<<<....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<
..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>
>>...>><..<<<<<....>>>>>...>>>>>>...>>>...>>>>....
.....>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......
>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<..
.............<<<<<....<<..>>.....>>>>><<<<<<.....<
<<...<<<<.....>>>>...>>>...>>>>>>............<<<<<
<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.....
..>>>>>>>.<<<<<.<<<..<<....>>>>>.<<<<<.......>>>>>
...............>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>
>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(((.[
[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.<<
<<...........<<<<<..<<<......<<<<.<<<....>>>.>>>>.
..>>>............>>>>>..>>>>.>>>>>>>>>>>...<<<.<<<
<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<.......>
>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<..
.....>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<<
....>>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.((..
>>>>..))>>>>>>>.............>>>>..]]>>>>...]]..)))
>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............
>>>>>>>.<<<<<....<<<...<<<<<<<<<<<))).>>>>>>..>>>>
>...>>>..>>>>>...<<<....<<<<<...........>>>>>....>
>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<..<<<
<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>..
.>>...>>>>>.>>>.....>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6gc4 Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		K2 Q39 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55
Binding residue
(residue number reindexed from 1)		K2 Q39 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gc4, PDBe:6gc4, PDBj:6gc4
PDBsum6gc4
PubMed29883607
UniProtP0A7M6|RL29_ECOLI Large ribosomal subunit protein uL29 (Gene Name=rpmC)

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