Structure of PDB 5nrl Chain Y Binding Site BS01

Receptor Information
>5nrl Chain Y (length=84) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMR
TIDQASLAQISLNGERFFGKPLKVEFSKSETKTL
Ligand information
>5nrl Chain 2 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugaaguguaguaucuguucuuuucaguguaacaacugaaau
gaccuaggcucauacacauuuuuuggcaggacgggaagaggagacgucgc
gacccucgcacgagucguucuugacuuggucgcuugauguuucuucuucc
cguuc
Receptor-Ligand Complex Structure
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PDB5nrl Structure of a pre-catalytic spliceosome.
Resolution7.2 Å
Binding residue
(original residue number in PDB)		Y31 S33 E37 K38 I39 N40 M41 Q42 R43 N64 Q68 R69 Q71 F73 S104 K105 S106 K109
Binding residue
(residue number reindexed from 1)		Y4 S6 E10 K11 I12 N13 M14 Q15 R16 N37 Q41 R42 Q44 F46 S77 K78 S79 K82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0030620 U2 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nrl, PDBe:5nrl, PDBj:5nrl
PDBsum5nrl
PubMed28530653
UniProtP40567|MSL1_YEAST U2 small nuclear ribonucleoprotein B'' (Gene Name=MSL1)

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