Structure of PDB 5lj3 Chain Y Binding Site BS01

Receptor Information
>5lj3 Chain Y (length=84) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMR
TIDQASLAQISLNGERFFGKPLKVEFSKSETKTL
Ligand information
>5lj3 Chain Z (length=171) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuguaa
caacugaaaugaccuaggcucauuguuacaauacacauuuuuuggggacg
ggaagaggagacgucgcgacccucgcagagucguucuugacuuggucgcu
ugauguuucuucuucccguuc
.............................................<<<<<
<<<......<<<<<<>>>.>>>>>>>>>>>...............<<<<<
<<<<<<.<<<<<<<<<<<<.<<.....<<<<<<....>>>>>>>>>>>>.
.>>>>>>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB5lj3 Cryo-EM structure of the spliceosome immediately after branching.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
Y31 E37 M41
Binding residue
(residue number reindexed from 1)
Y4 E10 M14
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0030620 U2 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:5lj3, PDBe:5lj3, PDBj:5lj3
PDBsum5lj3
PubMed27459055
UniProtP40567|MSL1_YEAST U2 small nuclear ribonucleoprotein B'' (Gene Name=MSL1)

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