Structure of PDB 5gpn Chain Y Binding Site BS01

Receptor Information
>5gpn Chain Y (length=672) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLV
EIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPI
CDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGA
LTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHED
INEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAGML
QSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAGTD
LRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLKVA
LIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSA
LQRSDGTAILAAVSNIAQNIRLSSGASQVAALDLGYKPGVEAIRKNPPKV
LFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSA
TYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRS
RLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDF
YMTDSISRASQTMAKCVKAVTE
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain5gpn Chain Y Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5gpn The architecture of the mammalian respirasome.
Resolution5.4 Å
Binding residue
(original residue number in PDB)		H124 C128 C131 Q133 C137 Q140 R175
Binding residue
(residue number reindexed from 1)		H94 C98 C101 Q103 C107 Q110 R145
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5gpn, PDBe:5gpn, PDBj:5gpn
PDBsum5gpn
PubMed27654917
UniProtA0A4X1V1H9

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