Structure of PDB 4kzz Chain Y Binding Site BS01

Receptor Information
>4kzz Chain Y (length=126) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIQEKLAKMYKTTP
DVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKT
SRKQRKERKNRMKKVRGTAKANVGAG
Ligand information
>4kzz Chain i (length=1797) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucuccuacuuggauaa
cugugguaauucuagagcuaauacaugccgacggcgcugacucccuuugu
gugggaugcgugcauuuaucagaucaaaaccaacccggucagccuccccg
ccggccggggggguggggcggcggcuuuggugacucuagauaaccucggg
ccgaucgcagcccuccguggcggcgacgacccauucgaacgucugcccua
ucaacuuucgaugguagucgccgugccuaccauggugaccacgggugacg
gggaaucaggguucgauuccggagagggagccugagaaacggcuaccaca
uccaaggaaggcagcaggcgcgcaaauuacccacucccgacccggggagg
uagugacgaaaaauaacaauacaggacucuuucgaggcccuguaauugga
augaguccacuuuaaauccuuuaacgaggauccauuggagggcaagucug
gucgcagcagccgcgguaauuccagcuccaauagcguauauuaaaguugc
ugcaguuaaaaagcucguaguuggaucuuggagggugcguagcgggccac
cgcccguccccgcccugccuccgaagcguuuacuuugaaaaaauuagagu
guucaaagcaggcccgagccgccuggauaccgcagcuaggaauaauggaa
uaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauuaa
gagggacggccgggggcauucguauugcgccgcuagaggugaaauucuug
gaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuuca
uuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucgua
guuccgaccauaaacgaugccgacuggcgaugcggcggcguuauucccau
gacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggggga
guaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccacca
ggaguggagccugcggcuuaauuugacucaacacgggaaaccucacccgg
cccggacacggacaggauugacagauugauagcucuuucucgauucugug
ggugguggugcauggccguucuuaguugguggagcgauuugucugguuaa
uuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccccg
agcggucggcgucccccaacuucuuagagggacaaguggcguucagccac
ccgagauugagcaauaacaggucugugaugcccuuagaugucggggcugc
acgcgcgcuacacugacuggcucagcgugugccuacccuacgccggcagg
cgcggguaacccguugaaccccauucgugauggggaucggggauugcaau
uauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugcg
uugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccgauu
ggaugguuuagugaggcccucggaucggcccgccggggucggcccacggc
ccuggcggagcgcugagaagacggucgaacuugacuaucuagaggaagua
aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>.........<<<...<<.<......
>.>>...>>>.[[..(((((.....<<<<<<<<<<<<.<...<.<<<...
.......>..>.>.>.....>>>>..............)))))......]
]...<<<<.<<<......>>>.>>>>....]]]...}}....]]].<<<.
...<<<....<<<<<<<.........>>>>>>>>>>......>>>...<<
<.<<<<....>>>>....>>>.}}.<<.<<<..........>>>.>>.<.
<<....>>.>...]]]]]].........<<<....<<<.....>>>..>>
>......}}.......<<<<<<<<<.<<<....>>>.>.>>>>>.>>>..
....<<..<...........>..>>.........<<<<<((......<<<
<.....<<..))>>.......>>>>.>>>>>..)))))).]]].......
.....{{.......{{...[[[.[[....<..<<<...<..<........
>..>...>>>..>...<<.<...>.>>..<<<<<..<.......<<...<
.......>.<<<<.......>>>>...>>......>..>>..>>>.....
..[[....(((((((.....>>>>>>>>>.)))))))...]]....]]..
..<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>...
...>>>>>>>.>.>>.......<<....>>...>>>>..>..>>>.>>>.
..]]]...}}......<<<<<<<...<...<<<<.<.....>.>>>>...
>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<......>
>>>>>>>>>.>..>>>...<<..}}>>...>>.....>>>.....<<<..
....<<<......>>>....>>>..]]]]..<<<<<.<<<<<<<..<<..
<<<<<..<<<.<<<<<<......<<........>>..........<<<<<
......<<<<<<.......<<.<<<........>>>.>>.....>>>>>>
.<.<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<....
..>>>...>>.>>>....<<<...<...<<<<..<<<<....<<<..<<<
<....>>>>.>>>....>>>>..>>>>..>.....<<<<<.....>>>>>
........>>>....>>>.>>>...>.>>>>>>>>.....>>>>>...>>
.>>>>.>>>.....<<.<<<........<.......<<<.<<<<....>>
>>.>>>....>.........>>>.>>............<<<<<.......
...>>>>>...........>>>>>.....<<<<<<<<.......>>>>>>
>>......>>...>>>>>>>>>>.>>.......<<.<..<<<<.<<....
<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<<<<.....>>>>
>>>>>>.>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>
...>.>>.........<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4kzz The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Resolution7.0305 Å
Binding residue
(original residue number in PDB)
R8 K11 F12 T14 K32 A33 K37 M47 G59 F60 T62 H63 F64 G65 G66 K84 S103 R104 K105 K108 K115 G119 T120 K122
Binding residue
(residue number reindexed from 1)
R6 K9 F10 T12 K30 A31 K35 M45 G57 F58 T60 H61 F62 G63 G64 K82 S101 R102 K103 K106 K113 G117 T118 K120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4kzz, PDBe:4kzz, PDBj:4kzz
PDBsum4kzz
PubMed23873042
UniProtG1TS40

[Back to BioLiP]