Structure of PDB 3qe9 Chain Y Binding Site BS01

Receptor Information
>3qe9 Chain Y (length=345) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEP
TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLL
KGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEA
DAQLAYLNKAGIVQAIITEDSALLAFGCKKVILKMDQFGNGLEIDQARLG
MCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIV
KVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAY
EDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3qe9 Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		G232 G234 A236 K237
Binding residue
(residue number reindexed from 1)		G231 G233 A235 K236
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0035312 5'-3' DNA exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3qe9, PDBe:3qe9, PDBj:3qe9
PDBsum3qe9
PubMed21496642
UniProtQ9UQ84|EXO1_HUMAN Exonuclease 1 (Gene Name=EXO1)

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