Structure of PDB 6zs9 Chain XI Binding Site BS01

Receptor Information
>6zs9 Chain XI (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQEEIGLI
RLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQ
VLKPFLEDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGG
CIDDTILSRQGFINYSKLPSLPLVQGELVGGLTCLTAQTHSLLQHQPLQL
TTLLDQYIREQ
Ligand information
>6zs9 Chain XA (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
aauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuugga
cacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauagua
ggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaa
aucccaaacauauaacugaacuccucacacccaauuggaccaaucuauca
cccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccuc
cgcauaagccugcgucagauaaccaacugacaauuaacagcccaauaucu
acaaucaaccaacaagucauuauuacccucacugucaacccaacacaggc
augcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuua
ccccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagagg
caccgccugcccagugacacauguuuaacggccgcgguacccuaaccgug
caaagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggc
uccacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugc
ccgugaagaggcgggcauaacacagcaagacgagaagacccuauggagcu
uuaauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguu
ggggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacu
ucaccagucaaagcgaaccucaauugauccaauaacuugaccaacggaac
aaguuacccuagggauaacagcgcaauccuauucuagaguccauaucaac
aauaggguuuacgaccucgauguuggaucaggacaucccgauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggaguaauccaggucgguuucuaucuacuuauuccucccugu
acgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccgu
aaaugauaucaucucaacuuagaauacccacacccacccaagaacagggu
u
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
..>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>
>...<<<......>>>....<<<.<<<...<..............<....
<<<.........>>>....>.......<<<......>>>...........
................>...>>>>>>........>>>>>>...<<<<<..
....>>>>>.........>>>>>><......<<..<<<....>>><<<<.
.<<<<........<<<<<........>>>>>......<<<...<<<<...
....................>>>>.......>>>.....<<......>>.
>>>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<
<<<<<..<<<.........>>>...<<<<<<.............>>>>>>
....<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>
........<...........<<<<<<.....>>>>>>.....>....>>>
....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<
<<<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<
..<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<
.....>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<
.....>>>>..>>>....>>.........<<<....>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<.......>>>>.....>>>>>..>...>>>.>>
....<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<.....
............>>>.>>><<<<<...<<<....>>>.>>>>>......<
<<................>>>..............<<<<.......>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zs9 Structural basis of mitochondrial translation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		K31 R35 R38 K46 A106 K124 V125 P127 N128 G149 H150
Binding residue
(residue number reindexed from 1)		K2 R6 R9 K17 A77 K95 V96 P98 N99 G120 H121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zs9, PDBe:6zs9, PDBj:6zs9
PDBsum6zs9
PubMed32812867
UniProtQ7Z7H8|RM10_HUMAN Large ribosomal subunit protein uL10m (Gene Name=MRPL10)

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