Structure of PDB 1vvj Chain XE Binding Site BS01

Receptor Information
>1vvj Chain XE (length=151) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLA
VQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGA
VPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG
E
Ligand information
>1vvj Chain XA (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguacuccguggucagcggcggacgggu
gaguaacgcgugggugaccuacccggaagagggggacaacccggggaaac
ucgggcuaaucccccauguggacccgccccuugggguguguccaaagggc
uuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggggua
auggcccaccaaggcgacgacggguagccggucugagaggauggccggcc
acaggggcacugagacacgggccccacuccuacgggaggcagcaguuagg
aaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaa
gaagcccuucgggguguaaacuccugaacccgggacgaaacccccgacga
ggggacugacgguaccgggguaauagcgccggccaacuccgugccagcag
ccgcgguaauacggagggcgcgagcguuacccggauucacugggcguaaa
gggcguguaggcggccuggggcgucccaugugaaagaccacggcucaacc
gugggggagcgugggauacgcucaggcuagacggugggagaggguggugg
aauucccggaguagcggugaaaugcgcagauaccgggaggaacgccgaug
gcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgugg
ggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgc
gcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgcc
gccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggc
ccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaacc
uuaccaggccuugacaugcuagggaacccgggugaaagccuggggugccc
cgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgugc
cgugagguguuggguuaagucccgcaacgagcgcaacccccgccguuagu
ugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcggga
ggaaggaggggacgacgucuggucagcauggcccuuacggccugggcgac
acacgugcuacaaugcccacuacaaagcgaugccacccggcaacggggag
cuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgacc
ccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaa
uacguucccgggccuuguacacaccgcccgucacgccaugggagcgggcu
cuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcccg
ugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcugg
a
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<....>>>>>>>>>.>>>>>......<<
.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......
>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<<<<
...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<...
....>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.
>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>..
......<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<...
...<<<<<..>>>>>.....>>>>....<<<<<........<<<<.....
>>>>..........>>>>>......<<<<<(((...<<<<<.....<<.)
))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((...
..<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>
>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<..
..<<<<<<<.<..<<<......>>>.....>.>>>>>>>...........
<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<
...<<...<<<<.........>>>>...>>>>>>>>..........<<<<
<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.
>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<
......>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<
<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<.
..<...<<<.....>>>.>....>>>>>>>.....<<<<<....>>>>>.
.......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>
.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>
>....>>>.....>>>>>>>......<....<<<<<<<........>>>>
>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<
<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>
>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>..
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1vvj Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Resolution3.44 Å
Binding residue
(original residue number in PDB)		R14 T16 A17 R18 M19 A21 G22 R24 R25 F45 K47 P49 K57 Y61 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 N130
Binding residue
(residue number reindexed from 1)		R10 T12 A13 R14 M15 A17 G18 R20 R21 F41 K43 P45 K53 Y57 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 N126
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1vvj, PDBe:1vvj, PDBj:1vvj
PDBsum1vvj
PubMed25128388
UniProtQ5SHQ5|RS5_THET8 Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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