Structure of PDB 7aoi Chain XC Binding Site BS01

Receptor Information
>7aoi Chain XC (length=584) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVSSRGPIVRWALSRPTSGLVSSPSEWRCGRDLSDEEKHSGLLLRIRDI
CQPLAKNDQLPVAVVKAQPSDLQVNEVDAVGDVAALSKVVKGKWRKISRQ
KTLLIEDDARTPFSDPSKSFSPRVQSYGEYVRLTGKLPRDLPVLRFVLYR
DSYSLNSVENRLGYVLSLQPDCVFLRDQPGGSFGCITQHGVCLGVTKEIL
SHASRHYNLHPLIFEPREYFSTDKLHSLLQGARGHHHRVLLRCVEGSQDT
IRALLKKTAERGFINYFWLDRFSVGTNRFFDMAVLAARGDYLKSIGALLH
CVAESNGVHYDHFLKYLNADPSTVPGIAQTWATTAKHMRSPNWIVQLLRG
LHKYHADAECGKSSYLAELWSALPMREALRRSAAEFVWNAMASQRLLSKG
LNVVEGDVVRMTFKITDVVLPVPYGSVAANNCLFPHLSPLDKKLYVEFAT
KHGMSFLFDEQMPSPLSNPLQFYRHLITKPVNMQVSVIRDPNSLTSIKSD
LAVMQERKLVQIGDIDYSTRVREPCVYNVSERFTEKMEEILKTHRGPNSV
VLSCYLPEDSSPFVMLREVFDLRHASFHDLYGLL
Ligand information
>7aoi Chain AA (length=758) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB7aoi Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
W94 R95 K96 R99 L103 R110 P112 Y130 Y164 R205 Y207 R339
Binding residue
(residue number reindexed from 1)
W94 R95 K96 R99 L103 R110 P112 Y130 Y164 R205 Y207 R339
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7aoi, PDBe:7aoi, PDBj:7aoi
PDBsum7aoi
PubMed33576519
UniProtD0A7A5

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