Structure of PDB 8fru Chain X Binding Site BS01

Receptor Information
>8fru Chain X (length=116) Species: 941442 (Giardia intestinalis assemblage A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTNVHFFRPKTLVHKKAPLYPRNPIKKGSWDDPCDLLRYPIKTDENTTQI
EKNNTIVFIVDRRASKPEIRKAFETVFETKVARVNTLITPLGLKKAFIRL
APDVQAMDVASKMGLA
Ligand information
>8fru Chain 4 (length=141) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacgccccgccggcggaugccucggcccgggcggcgacgaagagcgcggc
ggagcgcgagacgcggugcggacccgcccgccccgagaagcaccggcccu
cgaacgcagcgcgccccggcgccgccgccucggugcccugc
.........................................<<<<<<.((
.....>>>.....<<<<<<...<..))..>.........>>>>>>...>>
>....<<...>><<....>>.....................
Receptor-Ligand Complex Structure
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PDB8fru The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		T36 K40 K52 R88
Binding residue
(residue number reindexed from 1)		T11 K15 K27 R63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fru, PDBe:8fru, PDBj:8fru
PDBsum8fru
PubMed38242118
UniProtA8BMP6

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